Evidence map›Paper›PMID 38289876›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2024

Validation of a new 3D quantitative BOLD based cerebral oxygen extraction mapping.

Hyunyeol Lee, Jing Xu, Maria A Fernandez-Seara, Felix W Wehrli

Abstract readValidation Study
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Recent Advances in MR Imaging-based Quantification of Brain Oxygen Metabolism.Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hyunyeol LeeSchool of Electronic and Electrical Engineering, Kyungpook National University, Daegu, Republic of Korea.
Jing XuDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Maria A Fernandez-SearaDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Felix W WehrliDepartment of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Funding

High Spatial and Temporal Resolution MRI Mapping of Oxygen Consumption in HumansP41EB029460 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI Ravinder Reddy · 2021 to 2026
$7.6M
Simultaneous PET/MR Imaging of Brain Glucose and Oxygen Metabolism to Assess Energy Deficits Related to Alzheimer's Disease and the Response to InterventionR01NS131235 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI Keith St. Lawrence, Felix W Wehrli · 2024 to 2026
$1.4M
MRI-Based Regional Assessment of Cerebral Metabolism Via 3D Quantitative BOLDR21EB031364 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI WEHRLI, FELIX W · 2022 to 2023
$447k
NIBIB NIH HHS P41 EB029460NIBIB NIH HHS R21 EB031364NINDS NIH HHS R01 NS131235
6 · The paper itself

Abstract

Quantitative BOLD (qBOLD) MRI allows evaluation of oxidative metabolism of the brain based purely on an endogenous contrast mechanism. The method quantifies deoxygenated blood volume (DBV) and hemoglobin oxygen saturation level of venous blood (Y

Indexed as

Cerebrovascular CirculationHypercapniaMagnetic Resonance ImagingOxygenAdultBrainBrain MappingFemaleGray MatterHumansImaging, Three-DimensionalMaleOxygen ConsumptionReproducibility of ResultsYoung AdultOxygenBrain oxygen metabolismCalibrated BOLDCerebral metabolic rate of oxygenOxygen extraction fractionQuantitative BOLD

Identifiers

PMID38289876
PMCPMC11179617

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.