Evidence map›Paper›PMID 38293029›Full record

ArticlebioRxiv : the preprint server for biology2024

Morphologically defined substages of tail morphogenesis in

Karin Kiontke, Porfirio Fernandez, Alyssa Woronik, David H A Fitch

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Karin KiontkeDepartment of Biology, New York University, 100 Washington Square E., New York, NY 10003.ORCID 0000-0003-1588-4884
Porfirio FernandezDepartment of Biology, New York University, 100 Washington Square E., New York, NY 10003.ORCID 0009-0006-7118-6158
Alyssa WoronikSacred Heart University, 5151 Park Avenue, Fairfield, CT 06825.ORCID 0000-0003-3017-6069
David H A FitchDepartment of Biology, New York University, 100 Washington Square E., New York, NY 10003.ORCID 0000-0001-6940-7544
New York University · USSacred Heart University · US

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Control and Implementation of a Morphogenetic ProgramR01GM141395 · NIGMS · NEW YORK UNIVERSITY · PI FITCH, DAVID H. A. · 2021 to 2024
$1.6M
NIGMS NIH HHS R01 GM141395NIH HHS P40 OD010440
6 · The paper itself

Abstract

Background: Sex-specific morphogenesis occurs in Results: We here describe morphogenesis of the male tail at time points matching vulva development with special focus on morphogenesis of the tail tip. Using fluorescent reporters, we follow changes in cell shapes, cell fusions, nuclear migration, modifications in the basement membrane and formation of a new apical extracellular matrix at the end of the tail. Conclusion: Our analysis answers two open questions about tail tip morphogenesis (TTM) by showing that one of the four tail tip cells, hyp11, remains separate while the other cells fuse with each other and with two additional tail cells to form a ventral tail syncytium. This fusion begins early during TTM but is only completed towards the end of the process. This work provides a framework for future investigations of cell-biological factors that drive male tail morphogenesis.

Indexed as

apical extracellular matrixbasement membranecell fusionDevelopmental timingnuclear migration

Identifiers

PMID38293029
PMCPMC10827050
OpenAlexW4390840227

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.