Evidence mapPaperPMID 38295166Full record

ArticleScience advances2024

Targeting prostate tumor low-molecular weight tyrosine phosphatase for oxidation-sensitizing therapy.

Stephanie M Stanford, Tiffany P Nguyen, Joseph Chang, Zixuan Zhao, G Lavender Hackman, Eugenio Santelli, Colton M Sanders, Madhusudhanarao Katiki, Eleonora Dondossola, Brooke L Brauer and 16 more

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors at 10 institutions in 1 country.

Stephanie M StanfordDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-0934-5462
Tiffany P NguyenDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-0433-7167
Joseph ChangDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0009-0009-0944-3338
Zixuan ZhaoDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
G Lavender HackmanDepartment of Nutritional Sciences, College of Natural Sciences and Department of Pediatrics, Dell Medical School, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0001-7439-5138
Eugenio SantelliDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0002-8739-2750
Colton M SandersDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-1631-5122
Madhusudhanarao KatikiDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-4092-9386
Eleonora DondossolaDepartment of Genitourinary Medical Oncology and David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-6916-5418
Brooke L BrauerDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.
Michael A DiazDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-8211-9117
Yuan ZhanDepartment of Pediatrics and Department of Oncology, Dell Medical School, Livestrong Cancer Institutes, College of Natural Sciences, The University of Texas at Austin, Austin, TX USA.ORCID 0009-0001-2383-0408
Sterling H RamseyDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Philip A WatsonHuman Oncology and Pathogenesis Program, Memorial Sloan Kettering Cancer Center, New York, NY, USA.ORCID 0000-0002-6096-8254
Banumathi SankaranDepartment of Molecular Biophysics and Integrated Bioimaging, Berkeley Center for Structural Biology, Lawrence Berkeley National Laboratory, Berkeley, CA, USA.ORCID 0000-0002-3266-8131
Claudia PaindelliDepartment of Genitourinary Medical Oncology and David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Vanessa PariettiDepartment of Genitourinary Medical Oncology and David H. Koch Center for Applied Research of Genitourinary Cancers, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.ORCID 0000-0001-8170-6416
Antonios G MikosDepartment of Bioengineering, Rice University, Houston, TX, USA.ORCID 0000-0002-7264-2614
Alessia LodiDepartment of Nutritional Sciences, College of Natural Sciences and Department of Pediatrics, Dell Medical School, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-2104-5713
Aditya BagrodiaDepartment of Urology, University of California, San Diego, La Jolla, CA, USA.
Andrew ElliottDepartment of Clinical and Translational Research, Caris Life Sciences, Phoenix, AZ, USA.ORCID 0000-0001-8494-8031
Rana R McKayDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.
Ramachandran MuraliDepartment of Biomedical Sciences, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0002-8384-2793
Stefano TizianiDepartment of Nutritional Sciences, College of Natural Sciences and Department of Pediatrics, Dell Medical School, The University of Texas at Austin, Austin, TX, USA.ORCID 0000-0002-7230-0307
Arminja N KettenbachDepartment of Biochemistry and Cell Biology, Geisel School of Medicine at Dartmouth, Hanover, NH, USA.ORCID 0000-0003-3979-4576
Nunzio BottiniDepartment of Medicine, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-9025-7501
University of California San Diego · USCedars-Sinai Medical Center · USThe University of Texas MD Anderson Cancer Center · USDartmouth College · USLivestrong Foundation · USThe University of Texas at Austin · USCaris Life Sciences (United States) · USLawrence Berkeley National Laboratory · USMemorial Sloan Kettering Cancer Center · USRice University · US

Funding

The Patient-Reported Outcomes, Community-Engagement and Language (PRO-CEL) CoreP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · 1985 to 2025
$88.4M
Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · 1985 to 2025
$35.3M
User Training and OutreachP30GM124169 · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · 2025 to 2025
$3.3M
Role of LMPTP in cardiac fibrosisR01HL152717 · NHLBI · CEDARS-SINAI MEDICAL CENTER · PI Nunzio Bottini · 2023 to 2023
$563k
Mechanisms of Phosphorylation Signaling by Phosphoprotein PhosphatasesR35GM119455 · DARTMOUTH COLLEGE · 2025 to 2025
$443k
NCI NIH HHS P30 CA008748NCI NIH HHS P30 CA023108NCI NIH HHS R21 CA245621NHLBI NIH HHS R01 HL152717NIDDK NIH HHS R01 DK106233NIGMS NIH HHS P30 GM124169NIGMS NIH HHS R35 GM119455
6 · The paper itself

Abstract

Protein tyrosine phosphatases (PTPs) play major roles in cancer and are emerging as therapeutic targets. Recent reports suggest low-molecular weight PTP (LMPTP)-encoded by the

Indexed as

Prostatic NeoplasmsAnimalsHumansMaleMiceMolecular WeightProtein Tyrosine PhosphatasesTyrosineProtein Tyrosine PhosphatasesTyrosine

Identifiers

PMID38295166
PMCPMC10830117
OpenAlexW4391418267

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.