Evidence mapPaperPMID 38296478Full record

ArticleInternal medicine (Tokyo, Japan)2024

Significance of Persistent Systemic Support in the Clinical Course of Delayed Post-hypoxic Leukoencephalopathy Following Severe Coronavirus Disease 2019.

Juri Kawasaki, Naoko Mato, Hiroyuki Fujii, Kumiko Miura, Takafumi Mashiko, Shinshu Katayama, Yoshitaka Yamanouchi, Miki Sato, Toshikazu Takasaki, Ayako Takigami and 4 more

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Juri KawasakiDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Naoko MatoDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Hiroyuki FujiiDepartment of Radiology, Jichi Medical University, Japan.
Kumiko MiuraDivision of Neurology, Department of Medicine, Jichi Medical University, Japan.
Takafumi MashikoDivision of Neurology, Department of Medicine, Jichi Medical University, Japan.
Shinshu KatayamaDivision of Intensive Care, Department of Anesthesiology and Intensive Care Medicine, Jichi Medical University, Japan.
Yoshitaka YamanouchiDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Miki SatoPostgraduate Clinical Training Center, Jichi Medical University Hospital, Japan.
Toshikazu TakasakiDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Ayako TakigamiDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Shu HisataDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Shin NunomiyaDivision of Intensive Care, Department of Anesthesiology and Intensive Care Medicine, Jichi Medical University, Japan.
Koichi HagiwaraDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Makoto MaemondoDivision of Pulmonary Medicine, Department of Medicine, Jichi Medical University, Japan.
Jichi Medical University · JPJichi Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 45-year-old woman was hospitalized with severe coronavirus disease 2019 pneumonia. Following cytokine storm-induced multiorgan failure and lethal arrhythmia, the patient developed a sustained coma with flaccid quadriplegia. A cerebrospinal fluid examination excluded infectious and immunogenic encephalopathies, and diffusion-weighted magnetic resonance imaging demonstrated high-intensity areas in the white matter with a cortex-sparing distribution, suggesting delayed post-hypoxic leukoencephalopathy. As a result of intensive cardiopulmonary support for a month, the neurological function gradually recovered. Based on the reversible clinical course noted in this patient, accurate diagnosis and persistent medical approaches are important for the management of coronavirus disease 2019-related delayed post-hypoxic leukoencephalopathy.

Indexed as

COVID-19LeukoencephalopathiesDiffusion Magnetic Resonance ImagingDisease ProgressionFemaleHumansHypoxiaMagnetic Resonance ImagingMiddle Agedarrhythmiacoronavirus disease 2019 (COVID-19)cytokine stormdelayed post-hypoxic leukoencephalopathy (DPHL)multiorgan failure

Identifiers

PMID38296478
PMCPMC11081903
OpenAlexW4391378655

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.