Evidence map›Paper›PMID 38298161›Full record

ArticleGut microbes

Fungal signature differentiates alcohol-associated liver disease from nonalcoholic fatty liver disease.

Greta Viebahn, Phillipp Hartmann, Sonja Lang, Münevver Demir, Xinlian Zhang, Derrick E Fouts, Peter Stärkel, Bernd Schnabl

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. IntestinalJournal of clinical and translational hepatology · 2026
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Review
  11. Serum Levels ofMicroorganisms · 2025
    Article
  12. Review
  13. Review
  14. Microorganisms · 2025
    Article
  15. Review
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 3 countries.

Greta ViebahnDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Phillipp HartmannDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
Sonja LangFaculty of Medicine, University of Cologne, Cologne, Germany.
Münevver DemirDepartment of Hepatology and Gastroenterology, Campus Virchow Clinic and Campus Charité Mitte, Charité University Medicine, Berlin, Germany.
Xinlian ZhangDivision of Biostatistics and Bioinformatics, Herbert Wertheim School of Public Health and Human Longevity Science, University of California San Diego, La Jolla, CA, USA.
Derrick E FoutsDepartment of Genomic Medicine, J. Craig Venter Institute, Rockville, MD, USA.
Peter StärkelUniversité Catholique de Louvain, St. Luc University Hospital, Brussels, Belgium.
Bernd SchnablDepartment of Medicine, University of California San Diego, La Jolla, CA, USA.
University of California, San Diego · USCharité - Universitätsmedizin Berlin · DEJ. Craig Venter Institute · USRady Children's Hospital-San Diego · USUCLouvain · BEUniversity of Cologne · DE

Funding

UC San Diego Clinical and Translational Research InstituteUL1TR001442 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FIRESTEIN, GARY S, HOGARTH, MICHAEL · 2015 to 2024
$88.3M
The Southernearch Center for ALPD and CirrhosisP50AA011999 · NIAAA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIDEKAZU TSUKAMOTO · 1999 to 2026
$45.8M
UC San Diego Clinical and Translational Research InstituteKL2TR001444 · NCATS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DEPP, COLIN A. · 2015 to 2024
$15.4M
San Diego Digestive Diseases Research CenterP30DK120515 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI David Tevis Pride · 2019 to 2026
$10.8M
The Role of the Intestinal Mycobiome in Alcoholic Liver DiseaseR01AA024726 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2018 to 2026
$3.9M
Microbiome and intestinal innate immune response in alcoholic liver diseaseR01AA020703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHNABL, BERND G. · 2011 to 2020
$3.6M
Microbiome and Intestinal Innate Immune Response in Alcoholic Liver DiseaseR37AA020703 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Bernd G. Schnabl · 2021 to 2026
$2.5M
Developing Diverse Physician-Investigator Leaders for the Future of Child HealthK12HD105271 · NICHD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Gabriel G Haddad · 2021 to 2026
$1.8M
Microbiome as therapeutic target in alcoholic hepatitisU01AA026939 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FOUTS, DERRICK E, SCHNABL, BERND G. · 2018 to 2022
$1.7M
The role of pathobionts in alcoholic liver diseaseI01BX004594 · VA · VA SAN DIEGO HEALTHCARE SYSTEM · PI Bernd G. Schnabl · 2019 to 2026
–
BLRD VA I01 BX004594NCATS NIH HHS KL2 TR001444NCATS NIH HHS UL1 TR001442NIAAA NIH HHS P50 AA011999NIAAA NIH HHS R01 AA020703NIAAA NIH HHS R01 AA024726NIAAA NIH HHS R37 AA020703NIAAA NIH HHS U01 AA026939NICHD NIH HHS K12 HD105271NIDDK NIH HHS P30 DK120515
6 · The paper itself

Abstract

The fungal microbiota plays an important role in the pathogenesis of alcohol-associated liver disease (ALD) and nonalcoholic fatty liver disease (NAFLD). In this study, we aimed to compare changes of the fecal fungal microbiota between patients with ALD and NAFLD and to elucidate patterns in different disease stages between the two conditions. We analyzed fungal internal transcribed spacer 2 (ITS2) sequencing using fecal samples from a cohort of 48 patients with ALD, 78 patients with NAFLD, and 34 controls. The fungal microbiota differed significantly between ALD and NAFLD. The genera

Indexed as

Gastrointestinal MicrobiomeLiver Diseases, AlcoholicMycobiomeNon-alcoholic Fatty Liver DiseaseFibrosisHumansLiverLiver CirrhosisALDfungimicrobiomeMycobiomeNAFLD

Identifiers

PMID38298161
PMCPMC10841010
OpenAlexW4391447187

What Socratic holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.