Evidence map›Paper›PMID 38298658›Full record

ArticleHeliyon2024

G-quadruplex formation within the promoter region of

Ying Li, Zhichao He, Zewu Li, Yan Lu, Qingqing Xun, Longquan Xiang, Miaomiao Zhang

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Ying LiMedical Research Center, Affiliated Hospital of Jining Medical University, Jing Medical University, Jining, Shandong, 272000, PR China.
Zhichao HeMedical Equipment Department, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272000, PR China.
Zewu LiDepartment of Reproductive Medicine, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272000, PR China.
Yan LuClinical Laboratory Medicine Department, Jining No.1 People's Hospital, Jining, Shandong, 272000, PR China.
Qingqing XunSchool of Clinical Medicine, Jining Medical University, Jining, Shandong, 272000, PR China.
Longquan XiangDepartment of Pathology, Jining No.1 People's Hospital, Jining, Shandong, 272000, PR China.
Miaomiao ZhangMedical Research Center, Affiliated Hospital of Jining Medical University, Jing Medical University, Jining, Shandong, 272000, PR China.
Affiliated Hospital of Jining Medical University · CNJining First People's Hospital · CNJining Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

G-rich sequences in DNA and RNA tend to fold into stable secondary structures called G-quadruplexes. Except for the telomere region, G-quadruplex-forming sequences are widely present in gene promoters and have been implicated in transcriptional regulation. Single nucleotide polymorphisms (SNPs) can disrupt the G-quadruplex structure of a gene promoter. In this study, we confirmed the promoter of HSPB2, a cancer-related gene, tends to form an unusual DNA secondary structure. The dual luciferase assay revealed that the SNP rs2234704 in the

Indexed as

Breast cancerG-quadruplexHSPB2SNP

Identifiers

PMID38298658
PMCPMC10827768
OpenAlexW4390811432

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.