Evidence map›Paper›PMID 38299151›Full record

ReviewFrontiers in immunology2023

A double-edged sword: interactions of CX

Rana A Estaleen, Christopher M Reilly, Xin M Luo

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in immunology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Rana A EstaleenDepartment of Biomedical Sciences and Pathobiology, Virgnia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States.
Christopher M ReillyBiomedical Sciences, Edward Via College of Osteopathic Medicine, Blacksburg, VA, United States.
Xin M LuoDepartment of Biomedical Sciences and Pathobiology, Virgnia-Maryland College of Veterinary Medicine, Virginia Tech, Blacksburg, VA, United States.
Virginia–Maryland College of Veterinary Medicine · USEdward Via College of Osteopathic Medicine · US

Funding

Mechanistic role of probiotic Lactobacillus reuteri in autoimmune lupusR01AR073240 · NIAMS · VIRGINIA POLYTECHNIC INST AND ST UNIV · PI LUO, XIN · 2018 to 2022
$1.7M
NIAMS NIH HHS R01 AR073240
6 · The paper itself

Abstract

Systemic lupus erythematosus (SLE) is a systemic chronic disease initiated by an abnormal immune response to self and can affect multiple organs. SLE is characterized by the production of autoantibodies and the deposition of immune complexes. In regard to the clinical observations assessed by rheumatologists, several chemokines and cytokines also contribute to disease progression. One such chemokine and adhesion molecule is CX

Indexed as

Gastrointestinal MicrobiomeLupus Erythematosus, SystemicCX3C Chemokine Receptor 1CytokinesHumansInflammationReceptors, Complement 3bCR1 protein, humanCX3C Chemokine Receptor 1CytokinesReceptors, Complement 3bautoimmune diseaseautoimmunityCX3CR1gut microbiotalupuslupus nephritissystemic lupus erythematosus

Identifiers

PMID38299151
PMCPMC10828040
OpenAlexW4390953385

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.