Evidence mapPaperPMID 38299802Full record

ReviewClinical microbiology reviews2024

Evolving mechanisms and presentations of cardiovascular disease in people with HIV: implications for management.

Ilana Nazari, Matthew J Feinstein

Open access · greenAbstract readReview
In one paragraph

Review in Clinical microbiology reviews, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
15.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 22 citations in OpenAlex.

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  14. Clinical microbiology reviews · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ilana NazariNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-3074-9488
Matthew J FeinsteinNorthwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0002-8958-7666
Northwestern University · US

Funding

Immunologic, Inflammatory, and Clinical contributors to HIV-Related Heart Failure with Preserved Ejection Fraction (HFpEF)R01HL156792 · NHLBI · NORTHWESTERN UNIVERSITY · PI Matthew Joel Feinstein · 2023 to 2023
$733k
NHLBI NIH HHS R01 HL154862NHLBI NIH HHS R01 HL156792
6 · The paper itself

Abstract

People with HIV (PWH) are at elevated risk for cardiovascular diseases (CVDs), including myocardial infarction, heart failure, and sudden cardiac death, among other CVD manifestations. Chronic immune dysregulation resulting in persistent inflammation is common among PWH, particularly those with sustained viremia and impaired CD4+ T cell recovery. This inflammatory milieu is a major contributor to CVDs among PWH, in concert with common comorbidities (such as dyslipidemia and smoking) and, to a lesser extent, off-target effects of antiretroviral therapy. In this review, we discuss the clinical and mechanistic evidence surrounding heightened CVD risks among PWH, implications for specific CVD manifestations, and practical guidance for management in the setting of evolving data.

Indexed as

Cardiovascular DiseasesHIV InfectionsComorbidityHumanscardiovascular diseasehuman immunodeficiency virusinflammation

Identifiers

PMID38299802
PMCPMC10938901
OpenAlexW4391434674

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.