Evidence map›Paper›PMID 38303996›Full record

ArticleVeterinarni medicina2023

Ribavirin inhibits peste des petits ruminants virus proliferation

Weifeng Zhang, Hualong Deng, Yanfen Liu, Shaohong Chen, You Liu, Yuntao Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Veterinarni medicina, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Weifeng ZhangDepartment of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, P.R. China.
Hualong DengDepartment of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, P.R. China.
Yanfen LiuDepartment of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, P.R. China.
Shaohong ChenDepartment of Bioengineering, College of Food Science and Technology, Guangdong Ocean University, Zhanjiang, P.R. China.
You LiuDepartment of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, P.R. China.
Yuntao ZhaoDepartment of Animal Science, College of Coastal Agricultural Science, Guangdong Ocean University, Zhanjiang, P.R. China.
Guangdong Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peste des petits ruminants virus (PPRV), a member of the family Paramyxoviridae, belongs to the genus Morbillivirus. It causes devastating viral diseases in small ruminants and has been rapidly spreading over various regions in Africa, the Middle East, and Asia. Although vaccination is thought to be an effective management strategy against PPR infections, the heat sensitivity of PPRV vaccines severely restricts their use in regions with hot climates. In this research, we studied the antiviral activities of ribavirin and aimed to understand the potential mechanisms of action of ribavirin in the African green monkey kidney cells (Vero cells). In brief, the adsorption, intrusion, replication, and release of PPRV, as well as the mRNA expression level of RNA-dependent RNA polymerase (

Indexed as

antiviral activityantiviral drugsmechanismpeste des petits ruminantssignal pathway

Identifiers

PMID38303996
PMCPMC10828777
OpenAlexW4390225475

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.