Evidence map›Paper›PMID 38308185›Full record

ReviewUpdates in surgery2024

Progress in the study of mechanisms and pathways related to the survival of random skin flaps.

Xinghao Yin, Liang Feng, Qianqian Hua, Jiangtian Ye, Leyi Cai

Abstract readReview
PubMed Publisher
In one paragraph

Review in Updates in surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xinghao Yin *The Second School of Medicine, Wenzhou Medical University, Wenzhou, China.
Liang Feng *The Second School of Medicine, Wenzhou Medical University, Wenzhou, China.
Qianqian Hua *The First School of Medicine, Wenzhou Medical University, Wenzhou, China.
Jiangtian YeThe Second School of Medicine, Wenzhou Medical University, Wenzhou, China.
Leyi CaiThe Second School of Medicine, Wenzhou Medical University, Wenzhou, China. caileyi@wmu.edu.cn.

Funding

2022 National Undergraduate Innovation and Entrepreneurship Training Program 202210343021
6 · The paper itself

Abstract

The clinical application of random flaps in wound repair has been a topic of discussion. Random flaps are prone to necrosis due to the lack of well-defined vascular blood supply during transfer surgery. Their clinical utility is restricted, financial and psychological burdens is imposed on patients due to this limitation. The survival of random skin flaps depends on factors such as ischemia-reperfusion injury, oxidative stress, local inflammatory response, and neovascularization. This review aims to provide an overview of the evidence supporting the use of random flaps in clinical practice. In addition, this review explores the impact of different medications on signaling pathways within the flap's local microcirculation and investigates the interconnections between these pathways.

Indexed as

Graft SurvivalReperfusion InjurySurgical FlapsHumansInflammationMicrocirculationNeovascularization, PhysiologicOxidative StressSignal TransductionSkinWound HealingFlap survivalMolecular mechanismsRandom skin flapsSignaling pathway

Identifiers

PMID38308185

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.