Evidence mapPaperPMID 38308336Full record

Observational studyJournal of orthopaedic surgery and research2024

Ensemble learning-assisted prediction of prolonged hospital length of stay after spine correction surgery: a multi-center cohort study.

Wenle Li, Yusi Zhang, Xin Zhou, Xubin Quan, Binghao Chen, Xuewen Hou, Qizhong Xu, Weiheng He, Liang Chen, Xiaozhu Liu and 14 more

Registry-linked trialOpen access · goldAbstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of orthopaedic surgery and research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05867732 (A Multicenter Observational Cohort of Degenerative Spine Diseases in China), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05867732 completednot on this map

A Multicenter Observational Cohort of Degenerative Spine Diseases in China

Typeobservational_patient_registrySponsorXiamen UniversityRan2022 to 2023Enrolled10,000ConditionsDegenerative Spine Diseases
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Artificial Intelligence in Planning for Spine Surgery.Current reviews in musculoskeletal medicine · 2025
    Review
  3. Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 18 institutions in 1 country.

Wenle Li *State Key Laboratory of Molecular Vaccinology and Molecular, Diagnostics and Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China. drlee0910@163.com.ORCID http://orcid.org/0000-0002-2933-646X
Yusi Zhang *Cancer Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xin Zhou *Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, 030032, China.
Xubin QuanDepartment of Spinal Surgery, Guangxi Medical University Affiliated Liuzhou People's Hospital, Liuzhou, China.
Binghao ChenDepartment of Spinal Surgery, Guangxi Medical University Affiliated Liuzhou People's Hospital, Liuzhou, China.
Xuewen HouDepartment of Radiology, The First Dongguan Affiliated Hospital, Guangdong Medical University, Dongguan, China.
Qizhong XuDepartment of Radiology, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.
Weiheng HeDepartment of Radiology, People's Hospital of Ningxia Hui Autonomous Region, Yinchuan, China.
Liang ChenDepartment of Radiology, Hubei Provincial Hospital of Traditional Chinese Medicine, Wuhan, China.
Xiaozhu LiuDepartment of Critical Care Medicine, Beijing Shijitan Hospital, Capital Medical University, Beijing, China.
Yang ZhangCollege of Medical Informatics, Chongqing Medical University, Chongqing, China.
Tianyu XiangInformation Center, The University-Town Hospital of Chongqing Medical University, Chongqing, China.
Runmin LiDepartment of Foot and Ankle Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.
Qiang LiuDepartment of Orthopedics, Xianyang Central Hospital, Xianyang, Shannxi, China.
Shi-Nan WuEye Institute of Xiamen University, School of Medicine, Xiamen University, Xiamen, Fujian, China.
Kai WangKey Laboratory of Neurological Diseases, The Second Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, China.
Wencai LiuDepartment of Orthopedics, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, 200233, China.
Jialiang ZhengCancer Research Center, School of Medicine, Xiamen University, Xiamen, China.
Haopeng LuanDepartment of Spine Surgery, The Six Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.
Xiaolin YuDepartment of Orthopedics, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou, China.
Anfa ChenDepartment of Orthopedics, Jiangxi Province Hospital of Integrated Chinese and Western Medicine, Nanchang, China.
Chan XuState Key Laboratory of Molecular Vaccinology and Molecular, Diagnostics and Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Tongqing LuoDepartment of Spinal Surgery, Guangxi Medical University Affiliated Liuzhou People's Hospital, Liuzhou, China. luotongqing2929@sina.com.
Zhaohui HuDepartment of Spinal Surgery, Guangxi Medical University Affiliated Liuzhou People's Hospital, Liuzhou, China. 329870376@qq.com.
Fourth Affiliated Hospital of Guangxi Medical University · CNXiamen University · CNFirst Affiliated Hospital of Xi'an Jiaotong University · CNXuzhou Medical College · CNCapital Medical University · CNChongqing Medical University · CNGuangdong Medical College · CNGuiyang Medical University · CNHubei Provincial Hospital of Traditional Chinese Medicine · CNIntegrated Chinese Medicine (China) · CNLiuzhou General Hospital · CNShanghai Jiao Tong University · CNShanxi Medical University · CNShenzhen Second People's Hospital · CNThe Fourth People's Hospital of Ningxia Hui Autonomous Region · CNXi'an Honghui Hospital · CNXian Yang Central Hospital · CNXinjiang Medical University · CN

Funding

Liuzhou 2023 central guide local science and technology development fund project 2020J05297Shaanxi Provincial Health and Health Research Fund Project 2022E006
6 · The paper itself

Abstract

purposeThis research aimed to develop a machine learning model to predict the potential risk of prolonged length of stay in hospital before operation, which can be used to strengthen patient management.

methodsPatients who underwent posterior spinal deformity surgery (PSDS) from eleven medical institutions in China between 2015 and 2022 were included. Detailed preoperative patient data, including demographics, medical history, comorbidities, preoperative laboratory results, and surgery details, were collected from their electronic medical records. The cohort was randomly divided into a training dataset and a validation dataset with a ratio of 70:30. Based on Boruta algorithm, nine different machine learning algorithms and a stack ensemble model were trained after hyperparameters tuning visualization and evaluated on the area under the receiver operating characteristic curve (AUROC), precision-recall curve, calibration, and decision curve analysis. Visualization of Shapley Additive exPlanations method finally contributed to explaining model prediction.

resultsOf the 162 included patients, the K Nearest Neighbors algorithm performed the best in the validation group compared with other machine learning models (yielding an AUROC of 0.8191 and PRAUC of 0.6175). The top five contributing variables were the preoperative hemoglobin, height, body mass index, age, and preoperative white blood cells. A web-based calculator was further developed to improve the predictive model's clinical operability.

conclusionsOur study established and validated a clinical predictive model for prolonged postoperative hospitalization duration in patients who underwent PSDS, which offered valuable prognostic information for preoperative planning and postoperative care for clinicians. Trial registration ClinicalTrials.gov identifier NCT05867732, retrospectively registered May 22, 2023, https://classic. CLINICALTRIALS: gov/ct2/show/NCT05867732 .

Indexed as

AlgorithmsHospitalsCohort StudiesHumansLength of StayMachine LearningMachine learningMultimodalPosterior spinal deformity surgeryPostoperative length of staySpinal deformity

Identifiers

PMID38308336
PMCPMC10838003
OpenAlexW4391469821

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.