Evidence map›Paper›PMID 38310127›Full record

ArticleNature communications2024

Programmed microalgae-gel promotes chronic wound healing in diabetes.

Yong Kang, Lingling Xu, Jinrui Dong, Xue Yuan, Jiamin Ye, Yueyue Fan, Bing Liu, Julin Xie, Xiaoyuan Ji

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
60.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed, 243 citations in OpenAlex.

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  14. An orally deliverable CoMaterials today. Bio · 2026
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47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yong KangAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.ORCID 0000-0002-0151-8683
Lingling XuAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Jinrui DongAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Xue YuanAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Jiamin YeAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Yueyue FanAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China.
Bing LiuDepartment of Disease Control and Prevention, Rocket Force Characteristic Medical Center, Beijing, 10088, China. neaucn@126.com.
Julin XieDepartment of Burns, The First Affiliated Hospital of Sun Yat-Sen University, Guangzhou, 510080, China. xiejulin@mail.sysu.edu.cn.
Xiaoyuan JiAcademy of Medical Engineering and Translational Medicine, Medical College, Tianjin University, Tianjin, 300072, China. jixiaoyuan@tju.edu.cn.ORCID 0000-0002-6768-2304
Tianjin University · CNBeijing Center for Disease Prevention and Control · CNLinyi University · CNSun Yat-sen University · CN

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32071322
6 · The paper itself

Abstract

Chronic diabetic wounds are at lifelong risk of developing diabetic foot ulcers owing to severe hypoxia, excessive reactive oxygen species (ROS), a complex inflammatory microenvironment, and the potential for bacterial infection. Here we develop a programmed treatment strategy employing live Haematococcus (HEA). By modulating light intensity, HEA can be programmed to perform a variety of functions, such as antibacterial activity, oxygen supply, ROS scavenging, and immune regulation, suggesting its potential for use in programmed therapy. Under high light intensity (658 nm, 0.5 W/cm

Indexed as

Diabetes MellitusDiabetic FootMicroalgaeAnimalsAnti-Bacterial AgentsFemaleHydrogelsHypoxiaMiceOxygenReactive Oxygen SpeciesWound HealingAnti-Bacterial AgentsHydrogelsOxygenReactive Oxygen Species

Identifiers

PMID38310127
PMCPMC10838327
OpenAlexW4391515218

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.