ArticleJournal of the American Pharmacists Association : JAPhA
Patient activation and medication adherence in adults.
Article in Journal of the American Pharmacists Association : JAPhA. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 9 citations in OpenAlex.
- Breaking the cycle: patient activation role in improving diabetes self-care adherence for alleviating diabetes distress.The Libyan journal of medicine · 2026Article
- Latent profile analysis of medication adherence in lower extremity deep venous thrombosis-cross-sectional study.PloS one · 2026Article
- User perceptions of individually-tailored health information in digital apps: development of a scale.Frontiers in digital health · 2026Article
- Use and Discontinuation Rates of Long-Acting Injectable Antipsychotics Between Race/Ethnicity in Older Adults Using Medicaid Databases.Journal of the American Geriatrics Society · 2025Article
- Validation of the Patient Activation Measure in kidney stone disease patients.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2025Article
- Sociodemographic profile of patients treated by the Hemodynamics and Interventional Cardiology Service from Hospital São Paulo-Brazil.Revista da Associacao Medica Brasileira (1992) · 2025Observational
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Authors and funding
4 authors.
Funding
Abstract
backgroundPatients' level of medication adherence provides conflicting results in its relationship to patient activation. Multiple factors may be contributing to these mixed results.
objectivesThe primary purpose was to assess the association of patient activation to medication adherence in adults with chronic health conditions and low health literacy (HL). Secondary objectives were to determine whether age, education, gender, and race were associated with activation.
methodsParticipants completed self-report questionnaires regarding chronic disease self-management. Patient activation was measured using Hibbard's Patient Activation Measure (PAM). Self-report of medication adherence was determined using the Gonzalez-Lu adherence questionnaire. Block regressions first assessed the relation of demographic variables and education to adherence and then the added relation of patient activation in a second model.
resultsThe analyses included 301 participants (mean age 58 years; 53% female; mean chronic conditions of 6.6). Some of the most common chronic conditions included hypertension (60%), arthritis (51%), depression (49%), and hyperlipidemia (43%). The relation of older age to greater medication adherence was significant (P < 0.05) in both models. The addition of PAM was significantly related to better adherence (P < 0.001) and also increased the R squared value from 0.04 to 0.09. This change resulted in a moderate effect size (d = 0.50).
conclusionEvaluating patient activation at baseline may predict those more likely to be medication adherent in patients with low HL.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.