Evidence map›Paper›PMID 38321179›Full record

Trial reportScientific reports2024

Clinical effectiveness of orange peel polymethoxy-flavonoids rich fraction as a palatal dressing material compared to Alveogyl: randomized clinical trial.

Alzahraa A Alghriany, Ahmed U Ali, Iman S A Khallaf, Abeer S Hassan, Marwa A Sayed, Ahmed Mortada Fikry

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Citrus Flavonoids as Antimicrobials.Chemistry & biodiversity · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alzahraa A AlghrianyDepartment of Oral Medicine, Periodontology, and Diagnosis, Faculty of Dentistry, Assiut University, Assiut, Egypt. alghriany@aun.edu.eg.
Ahmed U AliDepartment of Pharmaceutics, Faculty of Pharmacy, Merit University, Sohag, Egypt.
Iman S A KhallafPharmacognosy and Natural Products Department, Faculty of Pharmacy, Menoufia University, Shibin Elkom, Egypt.
Abeer S HassanDepartment of Pharmaceutics, Faculty of Pharmacy, South Valley University, Qena, Egypt.
Marwa A SayedDepartment of Industrial Pharmacy, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Ahmed Mortada FikryDepartment of Oral Medicine, Periodontology, and Diagnosis, Faculty of Dentistry, Assiut University, Assiut, Egypt.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study assessed the clinical effectiveness of orange peel polymethoxy-flavonoids rich fraction (OPMF) solid dispersion as a palatal dressing material, compared with Alveogyl, in a randomized clinical trial. After harvesting free gingival grafts for 18 patients in three groups, the donor site in group I received OPMF; group II received Alveogyl; and group III received placebo dough material. The visual analog scale (VAS) pain score in group I showed the lowest value in week one without a significant difference. In week 2, there was a substantial decrease in pain in group I compared to group III. Week 4 showed reduced pain scores in all groups without significant differences. The results of the number of analgesic pills revealed, after 1 week, the lowest number of pills consumed in group I, with a considerable difference compared to group III. Healing process results showed that group I had the highest healing values in each interval, with a significant difference between group I and group III at 1 and 2 weeks. Color matching parameter showed slight differences between the groups' readings in favor of group I in all intervals without a statistically significant difference. The results suggest OPMF as a palatal dressing material that facilitates hemostasis, pain relief, and palatal wound healing.

Indexed as

Citrus sinensisBandagesHumansPostoperative PainTreatment OutcomeWound Healing

Identifiers

PMID38321179
PMCPMC10847459

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.