Evidence map›Paper›PMID 38321237›Full record

ArticlePediatric radiology2024

Evaluation of the effect of intraventricular haemorrhage on cerebral perfusion in preterm neonates using three-dimensional pseudo-continuous arterial spin labelling.

Chi Qin, Xin Zhao, Yanyong Shen, Yu Lu, Sike Li, Chunxiang Zhang, Xiaoan Zhang

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Article in Pediatric radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Chi QinDepartment of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0009-0007-5903-7982
Xin ZhaoDepartment of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0001-7525-4097
Yanyong ShenDepartment of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0009-0006-8965-7050
Yu LuDepartment of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0009-0001-1515-1448
Sike LiDepartment of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0009-0002-6035-0021
Chunxiang ZhangDepartment of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.ORCID 0000-0003-0467-6035
Xiaoan ZhangDepartment of Radiology, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China. zxa@zzu.edu.cn.ORCID 0000-0002-3156-0436

Funding

Scientific and technological key project of Henan Province Grant No.212102310742
6 · The paper itself

Abstract

backgroundIntraventricular haemorrhage (IVH) often arises as a cerebral complication directly related to preterm birth. The impaired autoregulation of cerebral blood flow is closely associated with IVH in preterm neonates. Three-dimensional pseudo-continuous arterial spin labelling (3D-pCASL) is a noninvasive magnetic resonance imaging (MRI) technique used for evaluating cerebral perfusion.

objectiveThis study aimed to compare cerebral blood flow values among three distinct groups using 3D-pCASL: preterm neonates with and without IVH and preterm neonates at term-equivalent age. MATERIALS AND

methodsA total of 101 preterm neonates who underwent conventional MRI and 3D-pCASL were included in this study. These neonates were categorised into three groups: 12 preterm neonates with IVH, 52 preterm neonates without IVH, and 37 healthy neonates at term-equivalent age. Cerebral blood flow measurements were obtained from six brain regions of interest (ROIs)-the frontal lobe, temporal lobe, parietal lobe, occipital lobe, basal ganglia, and thalamus-in the right and left hemispheres.

resultsThe cerebral blood flow values measured in all ROIs of preterm neonates with IVH were significantly lower than those of neonates at term-equivalent age (all P<0.05). Additionally, the cerebral blood flow in the temporal lobe was lower in preterm neonates without IVH than in neonates at term-equivalent age (16.87±5.01 vs. 19.76±5.47 ml/100 g/min, P=0.012). Furthermore, a noteworthy positive correlation was observed between post-menstrual age and cerebral blood flow in the temporal lobe (P=0.037), basal ganglia (P=0.010), and thalamus (P=0.010).

conclusionThe quantitative cerebral blood flow values, as measured by 3D-pCASL, highlighted that preterm neonates with IVH had decreased cerebral perfusion. This finding underscores the potential of 3D-pCASL as a technique for evaluating the developmental aspects of the brain in preterm neonates.

Indexed as

Cerebrovascular CirculationImaging, Three-DimensionalInfant, PrematureSpin LabelsCerebral HemorrhageFemaleHumansInfant, NewbornInfant, Premature, DiseasesMagnetic Resonance ImagingMaleSpin LabelsBrain developmentCerebral blood flowIntraventricular haemorrhageMagnetic resonance imagingPreterm neonatesThree-dimensional pseudo-continuous arterial spin labelling

Identifiers

PMID38321237

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.