Evidence map›Paper›PMID 38323078›Full record

ArticleOpen forum infectious diseases2024

Changes in Body Mass Index Over Time in People With and Without HIV Infection.

Jennifer O Lam, Wendy A Leyden, Stacey Alexeeff, Alexandra N Lea, Rulin C Hechter, Haihong Hu, Julia L Marcus, Lakecia Pitts, Qing Yuan, William J Towner and 2 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. DEFINE: A Prospective, Randomized, Phase 4 Trial to Assess a Protease Inhibitor-Based Regimen Switch Strategy to Manage Integrase Inhibitor-Related Weight Gain.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jennifer O LamDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.ORCID https://orcid.org/0000-0001-5650-4310
Wendy A LeydenDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Stacey AlexeeffDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Alexandra N LeaDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Rulin C HechterDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
Haihong HuMid-Atlantic Permanente Research Institute, Kaiser Permanente Mid-Atlantic States, Rockville, Maryland, USA.
Julia L MarcusDepartment of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-8552-414X
Lakecia PittsDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.
Qing YuanDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
William J TownerDepartment of Research and Evaluation, Kaiser Permanente Southern California, Pasadena, California, USA.
Michael A HorbergDepartment of Health Systems Science, Kaiser Permanente Bernard J. Tyson School of Medicine, Pasadena, California, USA.
Michael J SilverbergDivision of Research, Kaiser Permanente Northern California, Oakland, California, USA.

Funding

Electronic Health Record-Based Dementia Prediction for HIV Primary CareK01AI157849 · NIAID · KAISER FOUNDATION RESEARCH INSTITUTE · PI LAM, JENNIFER · 2021 to 2025
$713k
NIAID NIH HHS K01 AI157849
6 · The paper itself

Abstract

Background: Excess weight gain is an important health concern among people with HIV (PWH) on antiretroviral therapy (ART). The extent to which ART contributes to body mass index (BMI) changes is incompletely understood. Methods: We conducted a retrospective study of PWH initiating ART and demographically matched people without HIV (PWoH). Data on baseline BMI (kg/m Results: The study included 8256 PWH and 129 966 PWoH (mean baseline age, 40.9 and 42.2 years, respectively; 88% men). In adjusted models, the average annual change in BMI in the first 2 years after ART initiation was 0.53 for PWH and 0.12 for PWoH ( Conclusions: PWH initiating ART gained excess weight in the first 2 years, emphasizing the importance of monitoring weight and cardiometabolic health among ART-treated PWH.

Indexed as

antiretroviral therapybody mass indexcardiovascular diseasereturn to healthweight

Identifiers

PMID38323078
PMCPMC10846771

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.