Evidence map›Paper›PMID 38323609›Full record

ArticleeLife2024

Analysis of SMAD1/5 target genes in a sea anemone reveals ZSWIM4-6 as a novel BMP signaling modulator.

Paul Knabl, Alexandra Schauer, Autumn P Pomreinke, Bob Zimmermann, Katherine W Rogers, Daniel Čapek, Patrick Müller, Grigory Genikhovich

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Paul Knabl *Department of Neurosciences and Developmental Biology, University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0001-8834-565X
Alexandra Schauer *Department of Neurosciences and Developmental Biology, University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0001-7659-9142
Autumn P PomreinkeFriedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany.ORCID https://orcid.org/0000-0001-6160-6426
Bob ZimmermannDepartment of Neurosciences and Developmental Biology, University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-2354-0408
Katherine W RogersFriedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany.ORCID https://orcid.org/0000-0001-5700-2662
Daniel ČapekUniversity of Konstanz, Konstanz, Germany.ORCID https://orcid.org/0000-0001-5199-9940
Patrick MüllerFriedrich Miescher Laboratory of the Max Planck Society, Tübingen, Germany.ORCID https://orcid.org/0000-0002-0702-6209
Grigory GenikhovichDepartment of Neurosciences and Developmental Biology, University of Vienna, Vienna, Austria.ORCID https://orcid.org/0000-0003-4864-7770

Funding

Decoding developmental signaling during zebrafish embryogenesisZIAHD009002 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI ROGERS, KATHERINE · 2022 to 2025
$5.1M
Austrian Science Fund FWF P 32705European Research Council 637840European Research Council 863952
6 · The paper itself

Abstract

BMP signaling has a conserved function in patterning the dorsal-ventral body axis in Bilateria and the directive axis in anthozoan cnidarians. So far, cnidarian studies have focused on the role of different BMP signaling network components in regulating pSMAD1/5 gradient formation. Much less is known about the target genes downstream of BMP signaling. To address this, we generated a genome-wide list of direct pSMAD1/5 target genes in the anthozoan

Indexed as

Sea AnemonesAnimalsBody PatterningGene ExpressionGene Expression Regulation, DevelopmentalGenomeSignal TransductionBilateriaBMP signalingCnidariaDaniodevelopmental biologyevolutionary biologyevolution of axial patterningNematostellanematostella vectensiszebrafish

Identifiers

PMID38323609
PMCPMC10849676

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.