Evidence map›Paper›PMID 38327281›Full record

ReviewClinical kidney journal2024

Morphometric analysis of chronicity on kidney biopsy: a useful prognostic exercise.

Muhammad S Asghar, Aleksandar Denic, Andrew D Rule

Open access · goldAbstract readReview
In one paragraph

Review in Clinical kidney journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
4.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Guideline
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. MRI of kidney size matters.Magma (New York, N.Y.) · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Muhammad S AsgharDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Aleksandar DenicDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.ORCID https://orcid.org/0000-0001-9157-5405
Andrew D RuleDivision of Nephrology and Hypertension, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic · US

Funding

The macro- and micro- anatomy and pathology of the aging kidneyR01DK090358 · NIDDK · MAYO CLINIC ROCHESTER · PI ANDREW David RULE · 2011 to 2026
$9.9M
NIDDK NIH HHS R01 DK090358
6 · The paper itself

Abstract

Chronic changes on kidney biopsy specimens include increasing amounts of arteriosclerosis, glomerulosclerosis, interstitial fibrosis and tubular atrophy, enlarged nephron size, and reduced nephron number. These chronic changes are difficult to accurately assess by visual inspection but are reasonably quantified using morphometry. This review describes the various patient populations that have undergone morphometric analysis of kidney biopsies. The common approaches to morphometric analysis are described. The chronic kidney disease outcomes associated with various chronic changes by morphometry are also summarized. Morphometry enriches the characterization of chronicity on a kidney biopsy and this can supplement the pathologist's diagnosis. Artificial intelligence image processing tools are needed to automate the annotations needed for practical morphometric analysis of kidney biopsy specimens in routine clinical care.

Indexed as

CKDglomerulosclerosisinterstitial fibrosiskidney biopsynephrectomy

Identifiers

PMID38327281
PMCPMC10849190
OpenAlexW4391576587

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.