Evidence map›Paper›PMID 38328079›Full record

ArticlebioRxiv : the preprint server for biology2024

WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration.

Alyssa M Coulter, Valerie Cortés, Corey J Theodore, Rachel E Cianciolo, Ron Korstanje, Kenneth G Campellone

Open access · greenAbstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Alyssa M CoulterDepartment of Molecular & Cell Biology, Institute for Systems Genomics; University of Connecticut, Storrs CT, USA.
Valerie CortésThe Jackson Laboratory, Bar Harbor ME, USA.
Corey J TheodoreDepartment of Molecular & Cell Biology, Institute for Systems Genomics; University of Connecticut, Storrs CT, USA.
Rachel E CiancioloNiche Diagnostics LLC, Columbus OH, USA.
Ron KorstanjeThe Jackson Laboratory, Bar Harbor ME, USA.
Kenneth G CampelloneDepartment of Molecular & Cell Biology, Institute for Systems Genomics; University of Connecticut, Storrs CT, USA.
University of Connecticut · USJackson Laboratory · US

Funding

Translational CoreP30AG038070 · NIA · JACKSON LABORATORY · PI John Matthew Mahoney · 2010 to 2026
$19.3M
Genetic Factors that Influence Arsenic ToxicityR01ES029916 · NIEHS · JACKSON LABORATORY · PI CHURCHILL, GARY A, KORSTANJE, RONNY · 2019 to 2023
$3.6M
Causal connections between axon guidance proteins and early progressive kidney function decline in diabetesR01DK131061 · NIDDK · JOSLIN DIABETES CENTER · PI KROLEWSKI, ANDRZEJ S · 2022 to 2025
$2.7M
Identification of Kidney Disease Modifier Genes in Mouse and Human Alport SyndromeR01DK131019 · NIDDK · JACKSON LABORATORY · PI KORSTANJE, RONNY · 2022 to 2025
$1.5M
Cytoskeletal control of membrane remodelingR01GM107441 · NIGMS · UNIVERSITY OF CONNECTICUT STORRS · PI CAMPELLONE, KENNETH G · 2014 to 2018
$1.4M
Cytoskeletal functions in cell aging and diseaseK02AG050774 · NIA · UNIVERSITY OF CONNECTICUT STORRS · PI CAMPELLONE, KENNETH G · 2016 to 2021
$838k
NIA NIH HHS K02 AG050774NIA NIH HHS P30 AG038070NIDDK NIH HHS R01 DK131019NIDDK NIH HHS R01 DK131061NIEHS NIH HHS R01 ES029916NIGMS NIH HHS R01 GM107441
6 · The paper itself

Abstract

The actin cytoskeleton is essential for many functions of eukaryotic cells, but the factors that nucleate actin assembly are not well understood at the organismal level or in the context of disease. To explore the function of the actin nucleation factor WHAMM in mice, we examined how

Identifiers

PMID38328079
PMCPMC10849548
OpenAlexW4391127060

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.