Evidence map›Paper›PMID 38329552›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2024

Effectiveness of intraoral stents in reducing oral adverse events during radiotherapy for maxillary or nasal cavity malignant tumors.

Mao Kawakami, Nobuhiro Ueda, Kaori Yamaki, Kumiko Aoki, Nobuhide Wakai, Tetsuro Tamamoto, Isao Asakawa, Tadaaki Kirita

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Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Mao KawakamiDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, 634-8522, Japan.
Nobuhiro UedaDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, 634-8522, Japan. n-ueda@naramed-u.ac.jp.ORCID http://orcid.org/0000-0002-0929-4047
Kaori YamakiDepartment of Radiation Oncology, Nara Medical University, Kashihara, 634-8522, Japan.
Kumiko AokiDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, 634-8522, Japan.
Nobuhide WakaiDepartment of Radiation Oncology, Nara Medical University, Kashihara, 634-8522, Japan.
Tetsuro TamamotoDepartment of Radiation Oncology, Nara Medical University, Kashihara, 634-8522, Japan.
Isao AsakawaDepartment of Radiation Oncology, Nara Medical University, Kashihara, 634-8522, Japan.
Tadaaki KiritaDepartment of Oral and Maxillofacial Surgery, Nara Medical University, Kashihara, 634-8522, Japan.
Nara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMany patients experience oral adverse events during head and neck cancer radiotherapy (RT). The methods of management of such events are under debate. One such technique is the intraoral stent (IOS) technique, which removes normal tissue from the irradiation field. This retrospective study examined the factors associated with the occurrence of oral mucositis (OM) and dysgeusia and the efficacy of IOSs in preventing them.

methodsTwenty-nine patients who underwent RT in the maxilla or nasal cavity between 2016 and 2022 were included. They were investigated for background characteristics, treatment factors (IOS and dose-volume histogram), and oral adverse events (OM and dysgeusia).

resultsSignificant risk factors for the incidence of grade ≥ 2 (Common Terminology Criteria for Adverse Events v5.0) OM were the non-use of IOSs (p = 0.004) and diabetes (p = 0.025). A significant risk factor for the incidence of grade ≥ 1 dysgeusia was concomitant chemotherapy (p = 0.019). The radiation dose to the tongue was significantly lower in the IOS group than in the non-IOS group.

conclusionOur findings suggest that the use of an IOS during RT reduces the severity of OM by reducing irradiation to the tongue. Therefore, the use of an IOS is recommended during RT performed in the maxilla or nasal cavity.

Indexed as

NeoplasmsStomatitisDysgeusiaHumansMaxillaNasal CavityRetrospective StudiesStentsDysgeusiaHead and Neck cancerIntraoral stentOral adverse eventsOral mucositisRadiotherapy

Identifiers

PMID38329552
OpenAlexW4391647045

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.