Trial reportEnvironmental health perspectives2024
Effects of Daylong Exposure to Indoor Overheating on Thermal and Cardiovascular Strain in Older Adults: A Randomized Crossover Trial.
Trial report in Environmental health perspectives, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07656519 (Physiological Responses to Consecutive Days of Occupational Heat Exposure With and Without Overnight Access to Cooling), which is not on this map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Physiological Responses to Consecutive Days of Occupational Heat Exposure With and Without Overnight Access to Cooling
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Meta-analysis of heat-induced changes in cardiac function from over 400 laboratory-based heat exposure studies.Nature communications · 2025Pooled it
- Effect of pedestal fan use on serum stress biomarkers in older adults exposed to simulated daylong indoor overheating.Physiological reports · 2025Trial
- The physiology of survival: Heat.Experimental physiology · 2026Article
- Beyond the one-size-fits-all hydration recommendation for older adults: a call for more research on age-related change in thirst and hydration behavior.European journal of applied physiology · 2026Review
- Cardiovascular challenges of aging in a hotter environment: a narrative review.Journal of applied physiology (Bethesda, Md. : 1985) · 2025Review
- Ramping up the Heat: Induction of Systemic and Pulmonary Immune Responses and Metabolic Adaptations in Mice.bioRxiv : the preprint server for biology · 2025Article
- [The older population in the context of air pollution and climate change : Current vulnerability and prevention of associated risks].Zeitschrift fur Gerontologie und Geriatrie · 2025Article
- Evaluating compliance with HeatSuite for monitoring in situ physiological and perceptual responses and personal environmental exposure.NPJ digital medicine · 2025Article
- Validating new limits for human thermoregulation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Heat-Related Health Risks for People Experiencing Homelessness: A Rapid Review.Journal of urban health : bulletin of the New York Academy of Medicine · 2025Review
- Brain-derived neurotrophic factor in older adults exposed to simulated indoor overheating.European journal of applied physiology · 2025Article
- Respiratory and Cardiovascular Medical Emergency Calls Related to Indoor Heat Exposure through a Case-Control Study in New York City.Journal of urban health : bulletin of the New York Academy of Medicine · 2025Article
- Biophysical versus machine learning models for predicting rectal and skin temperatures in older adults.Journal of thermal biology · 2025Article
- Plasma epinephrine and norepinephrine responses to extreme heat exposures in young and older adults.American journal of physiology. Regulatory, integrative and comparative physiology · 2024Article
- Invited Perspective: Beating the Heat.Environmental health perspectives · 2024Article
- Indoor overheating: A review of vulnerabilities, causes, and strategies to prevent adverse human health outcomes during extreme heat events.Temperature (Austin, Tex.) · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHealth agencies recommend that homes of heat-vulnerable occupants (e.g., older adults) be maintained below 24-28°C to prevent heat-related mortality and morbidity. However, there is limited experimental evidence to support these recommendations.
objectiveTo aid in the development of evidence-based guidance on safe indoor temperatures for temperate continental climates, we evaluated surrogate physiological outcomes linked with heat-related mortality and morbidity in older adults during simulated indoor overheating.
methodsSixteen older adults [six women; median age: 72 y, interquartile range (IQR): 70-73 y; body mass index:
resultsCompared with 22°C, core temperature was elevated to a meaningful extent in 31°C [ DISCUSSION: Core temperature and cardiovascular strain were not appreciably altered following 8-h exposure to 26°C but increased progressively in conditions above this threshold. These data support proposals for the establishment of a 26°C indoor temperature upper limit for protecting vulnerable occupants residing in temperate continental climates from indoor overheating. https://doi.org/10.1289/EHP13159.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.