Evidence map›Paper›PMID 38333811›Full record

ArticleHeliyon2024

Modulation of immune cum inflammatory pathway by earthworm granulation tissue extract in wound healing of diabetic rabbit model.

Ahmed M E Elkhalifa, Sofi Imtiyaz Ali, Showkat Ul Nabi, Imran Bashir, Syed Taifa, Rabia Rakhshan, Iqra Hussain Shah, Muzafar Ahmad Mir, Masood Malik, Zahid Ramzan and 13 more

RetractedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
5.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors at 10 institutions in 3 countries.

Ahmed M E ElkhalifaDepartment of Public Health, College of Health Sciences, Saudi Electronic University, Riyadh, 11673, Saudi Arabia.
Sofi Imtiyaz AliPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Showkat Ul NabiPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Imran BashirDepartment of Sheep Husbandry, Srinagar, Jammu & Kashmir, 190006, India.
Syed TaifaPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Rabia RakhshanDepartment of Clinical Biochemistry, University of Kashmir, Srinagar, Jammu & Kashmir, 190006, India.
Iqra Hussain ShahPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Muzafar Ahmad MirPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Masood MalikPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Zahid RamzanPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Mehak NazarPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Nusrat BashirPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Shubeena AhadPreclinical Research Laboratory, Department of Clinical Veterinary Medicine, Ethics & Jurisprudence, Sher-e-Kashmir University of Agricultural Sciences and Technology (SKUAST-Kashmir), Srinagar, J&K, 190006, India.
Ibraq KhursheedDepartment of Zoology, Central University of Kashmir, 191201, Nunar, Ganderbal, Jammu & Kashmir, India.
Elham ElaminDepartment of Haematology, Faculty of Medical Laboratory Sciences, University of El Imam El Mahdi, Kosti, 1158, Sudan.
Elsharif A BaziePediatric Department, Faculty of Medicine, University of El Imam El Mahdi, Kosti, 1158, Sudan.
Nasser A N AlzerwiDepartment of Surgery, College of Medicine, Majmaah University, P. O. Box 66, Al-Majmaah, 11952, Riyadh, Kingdom of Saudi Arabia.
Musaed RayzahDepartment of Surgery, College of Medicine, Majmaah University, P. O. Box 66, Al-Majmaah, 11952, Riyadh, Kingdom of Saudi Arabia.
Bandar IdreesDepartment of Surgery, Prince Sultan Military Medical City in Riyadh, Makkah Al Mukarramah Rd, As Sulimaniyah, Saudi Arabia.
Fares RayzahDepartment of Surgery, Aseer Central Hospital, Abha, Saudi Arabia.
Yaser BakshDepartment of Surgery, Al-Iman General Hospital, Riyadh, Saudi Arabia.
Afnan AlsultanDepartment of Surgery, King Saud Medical City, Riyadh, Saudi Arabia.
Ahmed M AlzahraniDepartment of Surgery, College of Medicine, Majmaah University, P. O. Box 66, Al-Majmaah, 11952, Riyadh, Kingdom of Saudi Arabia.
Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir · INMajmaah University · SARiyadh Armed Forces Hospital · SAUniversity of El Imam El Mahdi · SDAsir Central Hospital · SACentral University of Kashmir · INKing Saud Medical City · SASaudi Electronic University · SAUniversity of Kashmir · INVeterinary & Animal Husbandry · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Regeneration is a rare occurrence in the animal kingdom, but the earthworm stands out as a remarkable example of this phenomenon. Recent research has highlighted the promising wound healing properties of extracts derived from earthworms. Therefore, we propose that earthworm granulation tissue extract (EGTE) may facilitate wound healing by regulating immune responses in a rabbit diabetic wound model. Electron microscopy reveals that 70 % EGTE possesses noteworthy porosity with spherical to irregularly oval configuration. Gas chromatography-mass spectrometry (GC-MS) Characterization of EGTE revealed higher levels of ergosta-5,7,22-trien-3-ol, (3. beta.,22E).

Indexed as

Inflammatory markersWound healingWound healing markers and oxidative stress

Identifiers

PMID38333811
PMCPMC10850419
OpenAlexW4391283894

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.