Evidence map›Paper›PMID 38334391›Full record

ArticlemSphere2024

PEXEL is a proteolytic maturation site for both exported and non-exported

Manuel A Fierro, Ajla Muheljic, Jihui Sha, James Wohlschlegel, Josh R Beck

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
5.4field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Flp/Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  7. Article
  8. Comparative analysis of codon usage patterns ofFrontiers in microbiology · 2023
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Manuel A FierroDepartment of Biomedical Sciences, Iowa State University, Ames, lowa, USA.ORCID 0000-0001-8729-5945
Ajla MuheljicRoy J. Carver Department of Biochemistry, Biophysics and Molecular Biology, Iowa State University, Ames, Iowa, USA.
Jihui ShaDepartment of Biological Chemistry, University of California, Los Angeles, California, USA.
James WohlschlegelDepartment of Biological Chemistry, University of California, Los Angeles, California, USA.
Josh R BeckDepartment of Biomedical Sciences, Iowa State University, Ames, lowa, USA.ORCID 0000-0001-6196-8689
Iowa State University · USUniversity of California, Los Angeles · US

Funding

Proteolytic Control of Iron Metabolism by the Ubiquitin Ligase FBXL5R01GM089778 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WOHLSCHLEGEL, JAMES AKIRA · 2010 to 2023
$4.0M
UIS2 function in establishing transport mechanisms at the malaria parasite-host cell interfaceR21AI173810 · NIAID · IOWA STATE UNIVERSITY · PI BECK, JOSH RYAN · 2023 to 2024
$412k
NIAID NIH HHS R21 AI173810NIGMS NIH HHS R01 GM089778
6 · The paper itself

Abstract

Obligate intracellular malaria parasites dramatically remodel their erythrocyte host through effector protein export to create a niche for survival. Most exported proteins contain a pentameric

Indexed as

Malaria, FalciparumPlasmodiumHumansPeptide HydrolasesPlasmodium falciparumProtozoan ProteinsPeptide HydrolasesProtozoan ProteinsexportPEXELPlasmepsin IXPlasmepsin VPlasmodiumRON11UIS2

Identifiers

PMID38334391
PMCPMC10900883
OpenAlexW4391683212

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.