Evidence map›Paper›PMID 38336659›Full record

ArticleBMC neurology2024

Cognitive function and quantitative electroencephalogram analysis in subjects recovered from COVID-19 infection.

Manal M Gaber, Hanan Hosny, Mona Hussein, Mona A Ashmawy, Rehab Magdy

Open access · goldAbstract read
In one paragraph

Article in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Manal M GaberClinical Neurophysiology Department, Neuro Diagnostic Research Center (NDRC), Beni-Suef University, Beni-Suef, Egypt.
Hanan HosnyClinical Neurophysiology Department, Neuro Diagnostic Research Center (NDRC), Beni-Suef University, Beni-Suef, Egypt.
Mona HusseinDepartment of Neurology, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt.
Mona A AshmawyClinical Neurophysiology Department, Neuro Diagnostic Research Center (NDRC), Beni-Suef University, Beni-Suef, Egypt.
Rehab MagdyDepartment of Neurology, Faculty of Medicine, Cairo University, Cairo, Egypt. rehab.m.hassan@kasralainy.edu.eg.ORCID http://orcid.org/0000-0002-4916-276X
Beni-Suef University · EGCairo University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND &

objectivesObjective assessment of post-COVID-19 cognitive dysfunction is highly warranted. This study aimed to evaluate the cognitive dysfunction of COVID-19 survivors with cognitive complaints, both clinically and neurophysiologically, using Quantitative Electroencephalogram (QEEG).

methodsThis case-control study was conducted on 50 recovered subjects from COVID-19 infection with cognitive complaints and 50 age, sex, and educational-matched healthy controls. Both groups were subjected to the following neurocognitive tests: Paired associate learning Test (PALT) and Paced Auditory Serial Addition Test (PASAT). The neurophysiological assessment was also done for both groups using QEEG.

resultsCOVID-19 survivors had significantly lower PALT scores than controls (P < 0.001). QEEG analysis found significantly higher levels of Theta / Beta ratio in both central and parietal areas in patients than in the controls (P < 0.001 for each). The interhemispheric coherence for the frontal, central, and parietal regions was also significantly lower in patients than in the control group regarding alpha and beta bands. There were statistically significant lower scores of PALT and PASAT among cases with severe COVID-19 infection (P = 0.011, 0.005, respectively) and those who needed oxygen support (P = 0.04, 0.01, respectively). On the other hand, a statistically significantly lower mean of frontal alpha inter-hemispheric coherence among patients with severe COVID-19 infection (P = 0.01) and those needing mechanical ventilation support (P = 0.04).

conclusionEpisodic memory deficit is evident in COVID-19 survivors with subjective cognitive complaints accompanied by lower inter-hemispheric coherence in frontal regions. These clinical and neurophysiological changes are associated with hypoxia and COVID-19 severity.

Indexed as

Cognitive DysfunctionCOVID-19Case-Control StudiesCognitionElectroencephalographyHumansCognitionPALTPASATPost-COVID-19QEEG

Identifiers

PMID38336659
PMCPMC10858500
OpenAlexW4391722678

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.