Evidence map›Paper›PMID 38338482›Full record

ReviewMolecules (Basel, Switzerland)2024

Phlorizin, an Important Glucoside: Research Progress on Its Biological Activity and Mechanism.

Tongjia Ni, Shuai Zhang, Jia Rao, Jiaqi Zhao, Haiqi Huang, Ying Liu, Yue Ding, Yaqian Liu, Yuchi Ma, Shoujun Zhang and 4 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
21.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Tongjia NiCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Shuai ZhangCollege of Chinese Medicinal Materials, Jilin Agricultural University, Changchun 130118, China.
Jia RaoCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Jiaqi ZhaoCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Haiqi HuangCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Ying LiuCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Yue DingCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Yaqian LiuCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Yuchi MaJilin Aodong Health Technology Co., Ltd., Yanbian 133700, China.
Shoujun ZhangJilin Aodong Yanbian Pharmaceutical Co., Ltd., Yanbian 133700, China.
Yang GaoJilin Jianwei Natural Biotechnology Co., Ltd., Linjiang 134600, China.
Liqian ShenJilin Jianwei Natural Biotechnology Co., Ltd., Linjiang 134600, China.
Chuanbo DingCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Yunpeng SunCollege of Traditional Chinese Medicine, Jilin Agriculture Science and Technology College, Jilin 132101, China.
Jilin Agricultural Science and Technology University · CNJilin Agricultural University · CNLuye Pharma (China) · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Phlorizin, as a flavonoid from a wide range of sources, is gradually becoming known for its biological activity. Phlorizin can exert antioxidant effects by regulating the IL-1β/IKB-α/NF-KB signaling pathway. At the same time, it exerts its antibacterial activity by reducing intracellular DNA agglutination, reducing intracellular protein and energy synthesis, and destroying intracellular metabolism. In addition, phlorizin also has various pharmacological effects such as antiviral, antidiabetic, antitumor, and hepatoprotective effects. Based on domestic and foreign research reports, this article reviews the plant sources, extraction, and biological activities of phlorizin, providing a reference for improving the clinical application of phlorizin.

Indexed as

GlucosidesPhlorhizinAntioxidantsFlavonoidsHypoglycemic AgentsAntioxidantsFlavonoidsGlucosidesHypoglycemic AgentsPhlorhizinbiological activityextraction and identificationmechanismphlorizin

Identifiers

PMID38338482
PMCPMC10856272
OpenAlexW4391565923

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.