Evidence map›Paper›PMID 38338823›Full record

ArticleInternational journal of molecular sciences2024

New Insights into Endogenous Retrovirus-K Transcripts in Amyotrophic Lateral Sclerosis.

Laura Moreno-Martinez, Sofía Macías-Redondo, Mark Strunk, María Isabel Guillén-Antonini, Christian Lunetta, Claudia Tarlarini, Silvana Penco, Ana Cristina Calvo, Rosario Osta, Jon Schoorlemmer

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Laura Moreno-MartinezLaboratory of Genetics and Biochemistry (LAGENBIO), Faculty of Veterinary, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0002-7277-4318
Sofía Macías-RedondoInstituto Aragonés de Ciencias de la Salud (IACS), Centro de Investigación Biomédica de Aragón (CIBA), 50009 Zaragoza, Spain.
Mark StrunkInstituto Aragonés de Ciencias de la Salud (IACS), Centro de Investigación Biomédica de Aragón (CIBA), 50009 Zaragoza, Spain.
María Isabel Guillén-AntoniniInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
Christian LunettaNEMO (NEuroMuscular Omnicentre) Clinical Center, Fondazione Serena Onlus, 20162 Milan, Italy.
Claudia TarlariniMedical Genetics Unit, Department of Laboratory Medicine, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy.
Silvana PencoMedical Genetics Unit, Department of Laboratory Medicine, ASST Grande Ospedale Metropolitano Niguarda, 20162 Milan, Italy.
Ana Cristina CalvoLaboratory of Genetics and Biochemistry (LAGENBIO), Faculty of Veterinary, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0001-5193-7782
Rosario OstaLaboratory of Genetics and Biochemistry (LAGENBIO), Faculty of Veterinary, University of Zaragoza, Miguel Servet 177, 50013 Zaragoza, Spain.ORCID 0000-0001-5687-6704
Jon SchoorlemmerInstituto de Investigación Sanitaria Aragón (IIS Aragón), 50009 Zaragoza, Spain.
Universidad de Zaragoza · ESAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITInstituto Aragonés de Ciencias de la Salud · ESFundacion Agencia Aragonesa para la Investigacion y el Desarrollo · ESInstituto de Investigación Sanitaria Aragón · ESIstituti Clinici Scientifici Maugeri · IT

Funding

Fundación Mehuer, Sevilla, Spain Ayuda de Colegios de Farmacéuticos
6 · The paper itself

Abstract

Retroviral reverse transcriptase activity and the increased expression of human endogenous retroviruses (HERVs) are associated with amyotrophic lateral sclerosis (ALS). We were interested in confirming

Indexed as

Amyotrophic Lateral SclerosisEndogenous RetrovirusesBrainBrain StemHumansLeukocytes, Mononuclearamyotrophic lateral sclerosiscopy-specific expressionendogenous retrovirusesNLRP3quantitative PCR

Identifiers

PMID38338823
PMCPMC10855536
OpenAlexW4391263078

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.