Evidence map›Paper›PMID 38339127›Full record

ReviewInternational journal of molecular sciences2024

Targeting PI3K/AKT/mTOR and MAPK Signaling Pathways in Gastric Cancer.

Diana-Theodora Morgos, Constantin Stefani, Daniela Miricescu, Maria Greabu, Silviu Stanciu, Silvia Nica, Iulia-Ioana Stanescu-Spinu, Daniela Gabriela Balan, Andra-Elena Balcangiu-Stroescu, Elena-Claudia Coculescu and 2 more

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 115 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
115citing papers in PubMed, 1 pooled it
30.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

115 citing papers in PubMed, 1 synthesis or guideline pooled it, 131 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Advances inOncology letters · 2026
    Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. The impact of the PI3K/AKT/mTOR signaling pathway on trastuzumab resistance in HER2-positive gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. CSIE: cancer subtyping via inference and ensemble.Briefings in bioinformatics · 2026
    Article
  17. Article
  18. Article
  19. Article
  20. Article

55 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Diana-Theodora MorgosDiscipline of Anatomy, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Constantin StefaniDepartment I of Family Medicine and Clinical Base, "Dr. Carol Davila" Central Military Emergency University Hospital, 010825 Bucharest, Romania.
Daniela MiricescuDiscipline of Biochemistry, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Maria GreabuDiscipline of Biochemistry, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Silviu StanciuDepartment of Internal Medicine and Gastroenterology, Carol Davila University of Medicine and Pharmacy, Central Military Emergency University Hospital, 010825 Bucharest, Romania.
Silvia NicaEmergency Discipline, University Hospital of Bucharest, 050098 Bucharest, Romania.ORCID 0000-0002-4491-0298
Iulia-Ioana Stanescu-SpinuDiscipline of Physiology, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Daniela Gabriela BalanDiscipline of Physiology, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Andra-Elena Balcangiu-StroescuDiscipline of Physiology, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Elena-Claudia CoculescuDiscipline of Oral Pathology, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 020021 Bucharest, Romania.
Dragos-Eugen GeorgescuDepartment of General Surgery, Faculty of Medicine, Carol Davila University of Medicine and Pharmacy, 50474 Bucharest, Romania.ORCID 0009-0005-5389-2254
Remus Iulian NicaCentral Military Emergency University Hospital "Dr. Carol Davila", 010825 Bucharest, Romania.ORCID 0000-0002-3722-6877
Carol Davila University of Medicine and Pharmacy · ROClinical Emergency Hospital Bucharest · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer (GC) is the fourth leading cause of death worldwide, with more than 1 million cases diagnosed every year.

Indexed as

Proto-Oncogene Proteins c-aktStomach NeoplasmsHumansMAP Kinase Signaling SystemPhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesSirolimusTOR Serine-Threonine KinasesPhosphatidylinositol 3-KinasePhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktSirolimusTOR Serine-Threonine Kinasesbacterial infectiondysregulationgastric cancergene mutationsinhibitorsMAPKPI3K/AKT/mTOR

Identifiers

PMID38339127
PMCPMC10856016
OpenAlexW4391539991

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.