Evidence mapPaperPMID 38339381Full record

ArticleCancers2024

The Impact of Physical Activity on the Outcomes of Active Surveillance in Prostate Cancer Patients: A Scoping Review.

Aldo Brassetti, Loris Cacciatore, Alfredo Maria Bove, Umberto Anceschi, Flavia Proietti, Leonardo Misuraca, Gabriele Tuderti, Rocco Simone Flammia, Riccardo Mastroianni, Maria Consiglia Ferriero and 7 more

Open access · goldAbstract readScoping Review
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 2 institutions in 1 country.

Aldo BrassettiIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.
Loris CacciatoreIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.
Alfredo Maria BoveIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-5139-9993
Umberto AnceschiIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-7586-4132
Flavia ProiettiIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-6478-8584
Leonardo MisuracaIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-6521-6289
Gabriele TudertiIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0003-4480-9090
Rocco Simone FlammiaIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-3129-0544
Riccardo MastroianniIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0003-3708-2209
Maria Consiglia FerrieroIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.
Giuseppe ChiacchioIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-8821-8201
Simone D'AnnunzioIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.
Rigoberto Pallares-MendezIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0001-6112-1672
Riccardo Lombardo"Sapienza" University of Rome, Department of Urology, Via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0003-2890-3159
Costantino LeonardoIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.
Cosimo De Nunzio"Sapienza" University of Rome, Department of Urology, Via di Grottarossa 1035, 00189 Rome, Italy.ORCID 0000-0002-2190-512X
Giuseppe SimoneIRCCS "Regina Elena" National Cancer Institute, Department of Urology, Via Elio Chianesi 53, 00144 Rome, Italy.ORCID 0000-0002-4868-9025
Istituti di Ricovero e Cura a Carattere Scientifico · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionActive surveillance has emerged as a valid therapeutic option in patients with low-risk prostate cancer, allowing for the deferral of definitive treatment until the time of possible disease progression. Although it is known that physical activity plays a protective role in the onset and progression of this tumor, its impact on patients with low-risk disease who are managed with active surveillance remains unclear. Our scoping review aims to summarize the existing evidence on this subject. EVIDENCE ACQUISITION: On 9 April 2023, a systematic search was conducted using the PubMed and Scopus databases. The search employed the combination of the following terms: ("prostate cancer" OR "prostate tumor") AND ("active surveillance") AND ("physical activity" OR "physical exercise" OR "physical intensive activity" OR "intensive exercise") AND ("lifestyle"). Out of the 506 identified articles, 9 were used for the present scoping review, and their results were reported according to the PRISMA-ScR statement. EVIDENCE SYNTHESIS: We discovered a lack of uniformity in the assessment of PA and its stratification by intensity. There was no consensus regarding what constitutes cancer progression in patients choosing expectant management. In terms of the impact of PA on AS outcomes, conflicting results were reported: some authors found no correlation, while others (six of total studies included) revealed that active men experience smaller increases in PSA levels compared to their sedentary counterparts. Additionally, higher levels of exercise were associated with a significantly reduced risk of PCa reclassification.

conclusionDue to the heterogeneity of the methodologies used in the available studies and the conflicting results reported, it is not possible to draw definitive conclusions concerning the role physical activity may play in the risk of prostate cancer progression in men managed with active surveillance.

Indexed as

active surveillancedisease progressionexerciselifestylephysical activityprostate cancer

Identifiers

PMID38339381
PMCPMC10854832
OpenAlexW4391432011

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.