ArticleClinical and experimental nephrology2024
Slope of the estimated glomerular filtration rate and its associated factors among individuals with chronic kidney disease in the general Japanese population.
Article in Clinical and experimental nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Heterogeneity of Estimated GFR Slopes According to Etiology, Estimated GFR and Urinary Albumin-to-Creatinine Ratio in a Large Cohort of Patients With CKD.Kidney international reports · 2026Article
- Twelve-Month Estimated Glomerular Filtration Rate Trajectory at the Time of Kidney Replacement Therapy Counseling Predicts Dialysis Initiation Within One Year.Journal of clinical medicine · 2025Article
- Approximation of Glomerular Filtration Rate after 1 Year Using Annual Medical Examination Data.Journal of clinical medicine · 2024Article
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2 authors.
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Abstract
backgroundTo suppress the incidence of end-stage kidney disease, we need to identify chronic kidney disease (CKD) patients with a high risk of rapid decline in the estimated glomerular filtration rate (eGFR). However, the current status of eGFR slope and its associated factors in the Japanese population have not been fully elucidated.
methodsAmong examinees aged 40-70 years in the 2014 Specific Health Checkup conducted by the National Health Insurance in Kobe, Japan (n = 61,985), we prospectively observed 7291 examinees with CKD stage G3 from 2014 to 2018.
resultsUntil 2018, 4221 examinees continued to undergo annual SHCs for a total of five checkups per subject and had available records of all necessary data. The median eGFR change was -0.22 ml/min/1.73 m
conclusionMost Japanese CKD stage-G3 subjects had a very slow decline in eGFR. A small proportion of CKD individuals who have a predictive factor of rapid eGFR decline should receive considerable attention from a nephrologist.
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