Trial reportEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2024
Dynamic Coronary Roadmap versus standard angiography for percutaneous coronary intervention: the randomised, multicentre DCR4Contrast trial.
Trial report in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04085614 (Dynamic Coronary Roadmap for Contrast Reduction), which is not on this map. Cited by 14 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Dynamic Coronary Roadmap for Contrast Reduction
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.
- Dynamic coronary roadmap in percutaneous coronary intervention: a systematic review and meta-analysis.BMC cardiovascular disorders · 2024Pooled it
- Dynamic coronary roadmap-guided versus traditional percutaneous coronary intervention techniques in contrast medium volume reduction: a systematic review and meta-analysis.The Egyptian heart journal : (EHJ) : official bulletin of the Egyptian Society of Cardiology · 2026Review
- From Electrocardiography to the Catheterization Laboratory: A Multimodal Artificial Intelligence Framework for Acute Coronary Syndrome Detection and Risk Stratification.Diagnostics (Basel, Switzerland) · 2026Review
- Metabolic Inflammation as a Common Thread in Cardio-Endocrine Diseases: Toward a Unified Therapeutic Framework.Cureus · 2026Review
- Advancements and challenges in autonomous endovascular interventional robotics: A comprehensive review.iScience · 2025Review
- Mitochondrial DNA methylation is involved in contrast-induced renal tubular epithelial cell injury.Renal failure · 2025Article
- Comparison of image quality in 40 keV virtual monoenergetic images of dual-energy CT pulmonary angiography using deep learning and iterative reconstruction algorithms under optimized low dose scanning protocols.Quantitative imaging in medicine and surgery · 2025Article
- Risk Prediction of Major Adverse Cardiovascular Events Within One Year After Percutaneous Coronary Intervention in Patients With Acute Coronary Syndrome: Machine Learning-Based Time-to-Event Analysis.JMIR medical informatics · 2025Observational
- Utilizing Mixed Reality Technology to Facilitate Coronary Chronic Total Occlusion Antegrade Wiring: A Pilot Study.JACC. Case reports · 2025Article
- Real-World Evaluation of PCI Guidance Using Dynamic Coronary Roadmap: A DCR4Contrast Trial Secondary Analysis.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Article
- Harnessing Artificial Intelligence for Innovation in Interventional Cardiovascular Care.Journal of the Society for Cardiovascular Angiography & Interventions · 2025Review
- Article
- Advancements and applications of artificial intelligence in cardiovascular imaging: a comprehensive review.European heart journal. Imaging methods and practice · 2024Review
- Study of fluoroscopic landmarks in IVUS guided zero contrast PCI - A single centre experience.Indian heart journalObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 6 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDecreasing the amount of iodinated contrast is an important safety aspect of percutaneous coronary interventions (PCI), particularly in patients with a high risk of contrast-induced acute kidney injury (CI-AKI). Dynamic Coronary Roadmap (DCR) is a PCI navigation support tool projecting a motion-compensated virtual coronary roadmap overlay on fluoroscopy, potentially limiting the need for contrast during PCI.
aimsThis study investigates the contrast-sparing potential of DCR in PCI, compared to standard angiographic guidance.
methodsThe Dynamic Coronary Roadmap for Contrast Reduction (DCR4Contrast) trial is a multicentre, international, prospective, unblinded, stratified 1:1 randomised controlled trial. Patients were randomised to either DCR-guided PCI or to conventional angiography-guided PCI. The primary endpoint was the total volume of iodinated contrast administered, and the secondary endpoint was the number of cineangiography runs during PCI.
resultsThe study population included 356 randomised patients (179 in DCR and 177 in control groups, respectively). There were no differences in patient demographics, angiographic characteristics or estimated glomerular filtration rate (eGFR) between the two groups. The total contrast volume used during PCI was significantly lower with DCR guidance compared with conventional angiographic guidance (64.6±44.4 ml vs 90.8±55.4 ml, respectively; p<0.001). The total number of cineangiography runs was also significantly reduced in the DCR group (8.7±4.7 vs 11.7±7.6 in the control group; p<0.001).
conclusionsCompared to conventional angiography-guided PCI, DCR guidance was associated with a significant reduction in both contrast volume and the number of cineangiography runs during PCI. (ClinicalTrials.gov: NCT04085614).
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.