Evidence map›Paper›PMID 38343395›Full record

ArticleIEEE control systems letters2022

An Anticipatory Scheme for the Model Predictive Control of Circadian Phase for Expected Environmental Light Changes.

Lindsey S Brown, Elizabeth B Klerman, Francis J Doyle

Abstract read
In one paragraph

Article in IEEE control systems letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lindsey S BrownHarvard John A. Paulson School of Engineering and Applied Sciences (SEAS), Allston, MA 02134, USA.
Elizabeth B KlermanDivision of Sleep Medicine, Harvard Medical School (HMS), Boston, MA 02115, USA and Division of Sleep and Circadian Disorders, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA.
Francis J DoyleHarvard SEAS and HMS Sleep Medicine.

Funding

TRAINING IN SLEEP, CIRCADIAN &RESPIRATORY NEUROBIOLOGYT32HL007901 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI Charles A Czeisler · 1998 to 2026
$18.5M
Sleep Duration Required to Restore Performance during Chronic Sleep RestrictionK24HL105664 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI KLERMAN, ELIZABETH B. · 2010 to 2019
$1.8M
NHLBI NIH HHS K24 HL105664NHLBI NIH HHS T32 HL007901
6 · The paper itself

Abstract

The circadian system is critical to timing biological functions in anticipation of daily environmental light changes, but much previous work on the development of molecular control inputs to shift the phase of the circadian system has applied model predictive control (MPC) without considering expected environmental light changes. We augment the MPC algorithm to develop an anticipatory control algorithm, which has advantages over MPC in achieving scheduled phase shifts (as occurs with jet lag and shiftwork). We further extend the algorithm in a model switching control scheme to account for changes in the light environment. Taken together, these two enhancements to the standard MPC framework allow for better control of the circadian oscillator in more realistic environments by anticipating environmental light changes.

Indexed as

predictive control for nonlinear systemssystems biology

Identifiers

PMID38343395
PMCPMC10857817

What Socratic holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.