ArticleAmerican journal of respiratory and critical care medicine2024
Molecular Phenotypes of Acute Respiratory Distress Syndrome in the ROSE Trial Have Differential Outcomes and Gene Expression Patterns That Differ at Baseline and Longitudinally over Time.
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Article in American journal of respiratory and critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
18.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 43 citations in OpenAlex.
- Early differential protein expression in blood and bronchoalveolar fluid among ARDS phenotypes.Scientific reports · 2026Trial
- Longitudinal multiomic signatures of ARDS and sepsis inflammatory phenotypes identify pathways associated with mortality.The Journal of clinical investigation · 2026Trial
- Heterogenous treatment effect of neuromuscular blocking agents for moderate-to-severe ARDS: a post hoc Markov model re-analysis of the ACURASYS trial.Intensive care medicine · 2025Trial
- Elastance May Determine the Neuromuscular Blockade Effect on Mortality in Acute Respiratory Distress Syndrome.American journal of respiratory and critical care medicine · 2025Trial
- Subphenotype-specific serum proteomic signatures in patients with ARDS.Journal of intensive care · 2026Article
- The Acute Respiratory Distress Syndrome (ARDS): epidemiology, etiology, molecular mechanisms, diagnosis and therapeutic strategies.Molecular biomedicine · 2026Review
- The molecular ICU: a primer on omics, informatics and the future of precision critical care.Critical care (London, England) · 2026Review
- Large-scale proteomic profiling identifies distinct inflammatory phenotypes in acute respiratory distress syndrome: a multicentre, prospective cohort study.The European respiratory journal · 2026Article
- A proteomics and redox proteomics approach to understanding ARDS heterogeneity.Scientific reports · 2026Article
- Artificial Intelligence- and Machine Learning-Assisted Subphenotyping for Personalized Immunotherapy in Sepsis.Journal of personalized medicine · 2026Review
- Observational
- Data-driven subphenotyping of severe ARDS patients requiring VV-ECMO.Frontiers in digital health · 2026Article
- Acute Respiratory Distress Syndrome Molecular Phenotypes Have Distinct Lower Respiratory Tract Transcriptomes.American journal of respiratory and critical care medicine · 2025Article
- Reply to SunAmerican journal of respiratory and critical care medicine · 2025Article
- High-temporal-resolution on-site multiplex biomarker monitoring in small animals using microfluidic digital ELISA.Biosensors & bioelectronics · 2025Article
- Increasing inflammatory biomarkers are associated with mortality in critically ill COVID-19 patients despite anti-inflammatory treatment.Clinical and experimental medicine · 2025Observational
- Biomarkers trajectories in critically ill patients with COVID-19 acute respiratory distress syndrome: insights from latent class growth analysis.BMC pulmonary medicine · 2025Article
- Two Physiologic Latent Classes of Acute Hypoxemic Respiratory Failure in Sepsis Are Distinguished by Lung Mechanics and Gas Exchange.Critical care explorations · 2025Article
- Temporal stability of phenotypes of acute respiratory distress syndrome: clinical implications for early corticosteroid therapy and mortality.Intensive care medicine · 2025Article
- Longitudinal multi-omic signatures of ARDS and sepsis inflammatory phenotypes identify key pathways associated with mortality.medRxiv : the preprint server for health sciences · 2025Article
Corrections and comments
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Authors and funding
16 authors at 7 institutions in 2 countries.
Pratik SinhaDivision of Clinical and Translational Research, Division of Critical Care, Department of Anesthesia, Washington University School of Medicine, St. Louis, Missouri.
Lucile NeytonDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.ORCID 0000-0003-1273-2228
Aartik SarmaDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Nelson WuDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Chayse JonesDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Hanjing ZhuoDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Kathleen D LiuDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Estella Sanchez GuerreroDivision of Infectious Diseases, Department of Medicine.
Rajani GhaleDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Christina LoveDivision of Infectious Diseases, Department of Medicine.
Eran MickDivision of Infectious Diseases, Department of Medicine.ORCID 0000-0002-7299-808X
Kevin L DelucchiDepartment of Psychiatry and Behavioral Sciences, and.
Charles R LangelierDivision of Infectious Diseases, Department of Medicine.
B Taylor ThompsonDivision of Pulmonary and Critical Care, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts.
Michael A MatthayDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Carolyn S CalfeeDivision of Pulmonary, Critical Care, Allergy and Sleep Medicine.
Advanced ENT and Allergy · USOffice of Infectious Diseases · USUniversity of California, San Francisco · USInstitute of Behavioral Sciences · JPMassachusetts General Hospital · USPediatric Nephrology of Alabama · USWashington University in St. Louis · US
Funding
Precision Medicine in the Acute Respiratory Distress SyndromeR35HL140026 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CALFEE, CAROLYN · 2018 to 2024
$6.8MPrecision Medicine in Sepsis with Critical IllnessR35GM142992 · NIGMS · WASHINGTON UNIVERSITY · PI Pratik Sinha · 2021 to 2026
$2.4MEvolution and resolution of ARDS molecular phenotypesK23HL163491 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Aartik Sarma · 2023 to 2026
$750kNHLBI NIH HHS K23 HL163491NHLBI NIH HHS R35 HL140026NIGMS NIH HHS GM142992NIGMS NIH HHS R35 GM142992
Abstract
PubMed holds no abstract for this paper.
Indexed as
Respiratory Distress SyndromeBiomarkersBlood ProteinsGene ExpressionHumansPhenotypeBiomarkersBlood ProteinsARDSmolecular phenotypesRNA sequencing
Identifiers
What Socratic holds
Textmetadata
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.