Evidence map›Paper›PMID 38346398›Full record

ReviewACS sensors2024

Label-Free Optical Imaging of Nanoscale Single Entities.

Xinyu Zhou, Andy Chieng, Shaopeng Wang

Abstract readReview
In one paragraph

Review in ACS sensors, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xinyu ZhouBiodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, Arizona 85287, United States.ORCID 0000-0003-1399-828X
Andy ChiengBiodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, Arizona 85287, United States.
Shaopeng WangBiodesign Center for Bioelectronics and Biosensors, Arizona State University, Tempe, Arizona 85287, United States.ORCID 0000-0002-2680-0503

Funding

Optical imaging of size, charge, mobility and binding of single proteinsR01GM140193 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI WANG, SHAOPENG · 2022 to 2025
$1.2M
NIGMS NIH HHS R01 GM140193
6 · The paper itself

Abstract

The advancement of optical microscopy technologies has achieved imaging of nanoscale objects, including nanomaterials, virions, organelles, and biological molecules, at the single entity level. Recently developed plasmonic and scattering based optical microscopy technologies have enabled label-free imaging of single entities with high spatial and temporal resolutions. These label-free methods eliminate the complexity of sample labeling and minimize the perturbation of the analyte native state. Additionally, these imaging-based methods can noninvasively probe the dynamics and functions of single entities with sufficient throughput for heterogeneity analysis. This perspective will review label-free single entity imaging technologies and discuss their principles, applications, and key challenges.

Indexed as

NanostructuresSurface Plasmon ResonanceMicroscopyOptical Imagingevanescent scatteringinterferometric scatteringlabel-free optical microscopynanofluidic scatteringnanoscale single entitiesplasmonic scatteringsingle moleculessurface plasmon resonance

Identifiers

PMID38346398
PMCPMC10990724

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.