Evidence map›Paper›PMID 38354239›Full record

ArticleScience advances2024

A mechanism of lysosomal calcium entry.

Matthew Zajac, Sourajit Mukherjee, Palapuravan Anees, Daphne Oettinger, Katharine Henn, Jainaha Srikumar, Junyi Zou, Anand Saminathan, Yamuna Krishnan

Open access · goldAbstract read
In one paragraph

Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Intracellular CaBiologia futura · 2025
    Review
  13. Article
  14. Review
  15. Review
  16. Article
  17. Metal Ion Signaling in Biomedicine.Chemical reviews · 2025
    Review
  18. Article
  19. Review
  20. Putative role of TMEM165 in congenital cardiomyopathies.Frontiers in molecular neuroscience · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Matthew ZajacDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-8282-2160
Sourajit MukherjeeDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-6561-6557
Palapuravan AneesDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
Daphne OettingerDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
Katharine HennDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
Jainaha SrikumarDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.
Junyi ZouDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-5005-737X
Anand SaminathanDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0002-9225-5558
Yamuna KrishnanDepartment of Chemistry, The University of Chicago, Chicago, IL 60637, USA.ORCID 0000-0001-5282-8852
University of Chicago · US

Funding

Intracellular Electrophysiology: An electrochemical atlas of organellesDP1GM149751 · NIGMS · UNIVERSITY OF CHICAGO · PI KRISHNAN, YAMUNA · 2022 to 2025
$5.7M
Mechanism and function of intracellular sodium-proton exchangersR01GM147197 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI KRISHNAN, YAMUNA, MIRSHAHI, TOORAJ · 2022 to 2025
$2.4M
Calcium homeostasis in organellesR01NS112139 · NINDS · UNIVERSITY OF CHICAGO · PI KRISHNAN, YAMUNA · 2020 to 2024
$1.8M
Mechanisms that alter Potassium channel trafficking in arrhythmiasR21HL161825 · NHLBI · UNIVERSITY OF CHICAGO · PI KRISHNAN, YAMUNA · 2022 to 2023
$448k
A mechanism of lysosomal Calcium entryR21NS114428 · NINDS · UNIVERSITY OF CHICAGO · PI KRISHNAN, YAMUNA · 2019 to 2020
$408k
NHLBI NIH HHS R21 HL161825NIGMS NIH HHS DP1 GM149751NIGMS NIH HHS R01 GM147197NINDS NIH HHS R01 NS112139NINDS NIH HHS R21 NS114428
6 · The paper itself

Abstract

Lysosomal calcium (Ca

Indexed as

CalciumCation Transport ProteinsAnimalsAntiportersCaenorhabditis elegansCalcium ChannelsCalcium SignalingHumansLysosomesMammalsSignal TransductionAntiportersCalciumCalcium ChannelsCation Transport ProteinsTMEM165 protein, human

Identifiers

PMID38354239
PMCPMC10866540
OpenAlexW4391807400

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.