Evidence map›Paper›PMID 38357482›Full record

ArticleHealth science reports2024

Fragmented QRS, a strong predictor of mortality and major arrhythmic events in patients with nonischemic cardiomyopathy: A systematic review and meta-analysis.

Moein Zangiabadian, Mohammad Sharifian Ardestani, Malihe Rezaee, Elahe Saberi Sharbabaki, Mahdi Nikoohemmat, Mohammad Eslami, Kian Goudarzi, Mojgan Sanjari, Mohammad Hasan Namazi, Mohammad Ali Akbarzadeh and 1 more

Abstract read
In one paragraph

Article in Health science reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Moein ZangiabadianEndocrinology and Metabolism Research Center Kerman University of Medical Sciences Kerman Iran.ORCID 0000-0002-7454-7944
Mohammad Sharifian ArdestaniCardiovascular Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.
Malihe RezaeeSchool of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.
Elahe Saberi SharbabakiSchool of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.
Mahdi NikoohemmatSchool of Medicine Arak University of Medical Sciences Arak Markazi Iran.
Mohammad EslamiDepartment of Pathology, Imam Hossein Educational Hospital, School of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.
Kian GoudarziSchool of Medicine Shahid Beheshti University of Medical Sciences Tehran Iran.
Mojgan SanjariEndocrinology and Metabolism Research Center Kerman University of Medical Sciences Kerman Iran.
Mohammad Hasan NamaziCardiovascular Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.
Mohammad Ali AkbarzadehCardiovascular Research Center Shahid Beheshti University of Medical Sciences Tehran Iran.
Azadeh AletahaEvidence Based Medicine Research Center, Endocrinology and Metabolism Clinical Sciences Institute Tehran University of Medical Sciences Tehran Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aims: Fragmented QRS (fQRS), which is associated with rhythm disturbances, can predispose the heart to fatal ventricular arrhythmias. Recently, accumulating studies indicates that fQRS is associated with poor prognosis in various types of cardiomyopathies. Therefore, we assessed the association between fQRS with all-cause mortality and major arrhythmic events (MAEs) in patients with nonischemic cardiomyopathy, in this systematic review and meta-analysis study. Methods: We performed a comprehensive search in databases of PubMed/Medline, EMBASE, and Web of Science from the beginning to December 31, 2022. Published observational studies (cohorts, case-control, or analytical cross-sectional studies) were included that report the prognostic value of fQRS in patients with different types of nonischemic cardiomyopathies for MAEs (sudden cardiac death, sudden cardiac arrest, sustained ventricular tachycardia [VT], ventricular fibrillation [VF], and appropriate shock) and all-cause mortality. We pooled risk ratios (RRs) through raw data and adjusted hazard ratios (aHRs) using "Comprehensive Meta-Analysis" software, Version 2.0. Results: Nineteen cohort and three analytical cross-sectional studies were included in this meta-analysis involving a total of 4318 subjects with nonischemic cardiomyopathy (1279 with fQRS and 3039 without fQRS). FQRS was significantly associated with an increased risk of all-cause mortality in patients with nonischemic cardiomyopathy (pooled RR: 1.920; 95% confidence interval [CI]: 1.388-2.656, Conclusion: Fragmented QRS could be a prognostic marker for all-cause mortality and MAEs in patients with various types of nonischemic cardiomyopathies, particularly HCM.

Indexed as

all‐cause mortalityfragmented QRSmajor arrhythmic eventsmeta‐analysisnonischemic cardiomyopathysystematic review

Identifiers

PMID38357482
PMCPMC10865277

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.