Evidence map›Paper›PMID 38360603›Full record

Observational studyBMC infectious diseases2024

Feasibility of wearable monitors to detect heart rate variability in children with hand, foot and mouth disease.

Le Nguyen Thanh Nhan, Nguyen Thanh Hung, Truong Huu Khanh, Nguyen Thi Thu Hong, Nguyen Thi Han Ny, Le Nguyen Truc Nhu, Do Duong Kim Han, Tingting Zhu, Tran Tan Thanh, Girmaw Abebe Tadesse and 4 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in BMC infectious diseases, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 3 countries.

Le Nguyen Thanh NhanChildren's Hospital Number 1, Ho Chi Minh City, Vietnam.
Nguyen Thanh HungChildren's Hospital Number 1, Ho Chi Minh City, Vietnam.
Truong Huu KhanhChildren's Hospital Number 1, Ho Chi Minh City, Vietnam.
Nguyen Thi Thu HongOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Nguyen Thi Han NyOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Le Nguyen Truc NhuOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Do Duong Kim HanOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Tingting ZhuDepartment of Engineering Science, University of Oxford, Oxford, UK.
Tran Tan ThanhOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Girmaw Abebe TadesseDepartment of Engineering Science, University of Oxford, Oxford, UK.
David CliftonDepartment of Engineering Science, University of Oxford, Oxford, UK.
H Rogier Van DoornOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Le Van TanOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
C Louise ThwaitesOxford University Clinical Research Unit, Ho Chi Minh City, Vietnam. lthwaites@oucru.org.
Oxford University Clinical Research Unit · VNUniversity of Oxford · GBChildren's Hospital 1 · VNAngkor Hospital for Children · KH

Funding

Wellcome TrustWellcome Trust 204904/Z/16/Z
6 · The paper itself

Abstract

Hand foot and mouth disease (HFMD) is caused by a variety of enteroviruses, and occurs in large outbreaks in which a small proportion of children deteriorate rapidly with cardiopulmonary failure. Determining which children are likely to deteriorate is difficult and health systems may become overloaded during outbreaks as many children require hospitalization for monitoring. Heart rate variability (HRV) may help distinguish those with more severe diseases but requires simple scalable methods to collect ECG data.We carried out a prospective observational study to examine the feasibility of using wearable devices to measure HRV in 142 children admitted with HFMD at a children's hospital in Vietnam. ECG data were collected in all children. HRV indices calculated were lower in those with enterovirus A71 associated HFMD compared to those with other viral pathogens.HRV analysis collected from wearable devices is feasible in a low and middle income country (LMIC) and may help classify disease severity in HFMD.

Indexed as

EnterovirusEnterovirus A, HumanEnterovirus InfectionsHand, Foot and Mouth DiseaseChildChinaFeasibility StudiesHeart RateHumansInfantHand foot and mouth diseaseHeart rate variabilityVietnamWearable devices

Identifiers

PMID38360603
PMCPMC10868055
OpenAlexW4391842883

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.