Evidence map›Paper›PMID 38365841›Full record

ArticleeNeuro2024

Synaptotagmin-7 Counteracts Short-Term Depression during Phasic Dopamine Release.

Joseph J Lebowitz, Sarah A Kissiwaa, Kim A Engeln, Anna M Bowman, John T Williams, Skyler L Jackman

Open access · goldAbstract read
In one paragraph

Article in eNeuro, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. The Synaptic Vesicle Priming Protein Munc13 Mediates Evoked Somatodendritic Dopamine Release.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
  2. Article
  3. Article
  4. Synaptotagmin-1 is a CaCell reports · 2023
    Article
  5. Synaptotagmins 1 and 7 Play Complementary Roles in Somatodendritic Dopamine Release.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Joseph J LebowitzVollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098.
Sarah A KissiwaaVollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098.
Kim A EngelnVollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098.
Anna M BowmanVollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098.
John T WilliamsVollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098.ORCID https://orcid.org/0000-0002-0647-6144
Skyler L JackmanVollum Institute, Oregon Health & Science University, Portland, Oregon 97239-3098 jackmans@ohsu.edu.
Oregon Health & Science University · US

Funding

BIOLOGICAL BASES OF DRUG-SEEKING BEHAVIORT32DA007262 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAMS, JOHN T · 1991 to 2022
$9.4M
COCAINE: EFFECTS ON SINGLE NEURONSR01DA004523 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI WILLIAMS, JOHN T · 1987 to 2025
$7.6M
The mechanisms and functions of short-term synaptic plasticityR01NS135048 · NINDS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Skyler Lofstrand Jackman · 2024 to 2026
$1.3M
NIDA NIH HHS R01 DA004523NIDA NIH HHS T32 DA007262NINDS NIH HHS R01 NS135048
6 · The paper itself

Abstract

Dopamine neurons switch from tonic pacemaker activity to high-frequency bursts in response to salient stimuli. These bursts lead to superlinear increases in dopamine release, and the degree of this increase is highly dependent on firing frequency. The superlinearity and frequency dependence of dopamine release implicate short-term plasticity processes. The presynaptic Ca

Indexed as

DepressionDopamineAnimalsCalciumDopaminergic NeuronsMiceSynapsesSynaptotagminsCalciumDopamineSynaptotagminsSyt7 protein, mousedopamineshort-term plasticitysynaptotagmin

Identifiers

PMID38365841
PMCPMC10932592
OpenAlexW4391878161

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.