Evidence map›Paper›PMID 38374298›Full record

ReviewNature reviews. Immunology2024

The regulation and differentiation of regulatory T cells and their dysfunction in autoimmune diseases.

Tomokazu S Sumida, Nardos T Cheru, David A Hafler

Open access · greenAbstract readReview
In one paragraph

Review in Nature reviews. Immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 131 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
131citing papers in PubMed, 1 pooled it
33.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

131 citing papers in PubMed, 1 synthesis or guideline pooled it, 139 citations in OpenAlex.

  1. Research progress on T-cell responses inFrontiers in microbiology · 2026
    Pooled it
  2. Trial
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  4. Article
  5. Head and neck squamous cell carcinoma: current and emerging therapeutic strategies.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
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  10. The long-lived immune system of centenarians.Nature reviews. Immunology · 2026
    Review
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71 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Tomokazu S SumidaDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA. tomokazu.sumida@yale.edu.ORCID http://orcid.org/0000-0002-9806-2642
Nardos T CheruDepartment of Immunobiology, Yale School of Medicine, New Haven, CT, USA.
David A HaflerDepartment of Neurology, Yale School of Medicine, New Haven, CT, USA. david.hafler@yale.edu.ORCID http://orcid.org/0000-0003-4664-535X
Yale University · USBroad Institute · US

Funding

Role of Negative Costimulation in Regulation of AutoimmunityP01AI039671 · NIAID · YALE UNIVERSITY · PI VIJAY K. KUCHROO · 1996 to 2026
$51.7M
Systems investigation of vaccine responses in B cell depleted autoimmune patientsU19AI089992 · NIAID · YALE UNIVERSITY · PI Albert C Shaw · 2010 to 2026
$50.4M
Yale SPORE in Skin CancerP50CA121974 · NCI · YALE UNIVERSITY · PI MARCUS W BOSENBERG, Harriet M. Kluger · 2006 to 2026
$43.9M
Transgenic / Knock-out mouse coreP01AI073748 · NIAID · BRIGHAM AND WOMEN'S HOSPITAL · PI HAFLER, DAVID A. · 2008 to 2019
$17.1M
(8) Mechanisms of autoimmune endocrine diseases in patients receiving checkpoint inhibitorsR01CA227473 · NCI · YALE UNIVERSITY · PI HEROLD, KEVAN C, KLUGER, HARRIET M. · 2018 to 2022
$3.2M
Human and Translational Immunology Training ProgramT32AI155387 · NIAID · YALE UNIVERSITY · PI Joseph Edgar Craft, Kevan C Herold · 2021 to 2026
$2.6M
Yale Clinical Neuroscientist Training ProgramR25NS079193 · NINDS · YALE UNIVERSITY · PI HAFLER, DAVID A. · 2012 to 2023
$943k
NCI NIH HHS P50 CA121974NCI NIH HHS R01 CA227473NIAID NIH HHS P01 AI039671NIAID NIH HHS P01 AI073748NIAID NIH HHS T32 AI155387NIAID NIH HHS U19 AI089992NINDS NIH HHS R25 NS079193
6 · The paper itself

Abstract

The discovery of FOXP3

Indexed as

Autoimmune DiseasesCell DifferentiationForkhead Transcription FactorsT-Lymphocytes, RegulatoryAnimalsHumansMiceForkhead Transcription FactorsFOXP3 protein, human

Identifiers

PMID38374298
PMCPMC11216899
OpenAlexW4391925509

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.