Evidence map›Paper›PMID 38388424›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Nacc1 Mutation in Mice Models Rare Neurodevelopmental Disorder with Underlying Synaptic Dysfunction.

Mark A Deehan, Josine M Kothuis, Ellen Sapp, Kathryn Chase, Yuting Ke, Connor Seeley, Maria Iuliano, Emily Kim, Lori Kennington, Rachael Miller and 9 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Cytoplasmic region of beta-dystroglycan is essential for postsynaptic maturation and neuromuscular function in mice.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  2. Article
  3. Nucleus Accumbens Associated Protein 1 in Cancers-The Real Value.International journal of molecular sciences · 2024
    Article
  4. Loss-of-function of the Zinc Finger Homeobox 4 (medRxiv : the preprint server for health sciences · 2024
    Article
  5. Case report: A novelFrontiers in psychiatry · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 3 institutions in 1 country.

Mark A DeehanDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.ORCID 0000-0002-6510-9918
Josine M KothuisDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.
Ellen SappDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.ORCID 0000-0002-0905-4940
Kathryn ChaseDepartment of Medicine, UMass Chan Medical School, Worcester, Massachusetts 01655.
Yuting KeDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.
Connor SeeleyDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.
Maria IulianoDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.
Emily KimDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.
Lori KenningtonDepartment of Medicine, UMass Chan Medical School, Worcester, Massachusetts 01655.
Rachael MillerDepartment of Medicine, UMass Chan Medical School, Worcester, Massachusetts 01655.
Adel BoudiDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.ORCID 0000-0002-3599-3124
Kai ShingDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.ORCID 0000-0002-9321-6382
Xueyi LiDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.
Edith PfisterDepartment of Medicine, UMass Chan Medical School, Worcester, Massachusetts 01655.
Christelle AnacletDepartment of Neurological Surgery, University of California Davis School of Medicine, Davis, California 95817.
Michael BrodskyDepartment of Molecular, Cell and Cancer Biology, UMass Chan Medical School, Worcester, Massachusetts 01655.
Kimberly Kegel-GleasonDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129.ORCID 0000-0003-4692-5829
Neil AroninDepartment of Medicine, UMass Chan Medical School, Worcester, Massachusetts 01655.
Marian DiFigliaDepartment of Neurology, Massachusetts General Hospital, Charlestown, Massachusetts 02129 difiglia@helix.mgh.harvard.edu.
Massachusetts General Hospital · USUniversity of Massachusetts Chan Medical School · USUniversity of California, Davis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A missense mutation in the transcription repressor Nucleus accumbens-associated 1 (

Indexed as

Autistic DisorderTranscription FactorsAnimalsFemaleHumansMaleMiceMutationNeoplasm ProteinsNerve Tissue ProteinsProtein IsoformsRepressor ProteinsWeight GainNACC1 protein, humanNacc1 protein, mouseNeoplasm ProteinsNerve Tissue ProteinsProtein IsoformsRepressor ProteinsTranscription FactorsautismEEGNACC1seizuresynapsetranscriptomics

Identifiers

PMID38388424
PMCPMC10993038
OpenAlexW4392028313

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.