Evidence map›Paper›PMID 38391539›Full record

ReviewAntibiotics (Basel, Switzerland)2024

Antibiotic Therapy for Active Crohn's Disease Targeting Pathogens: An Overview and Update.

Gaetano Iaquinto, Giuseppe Mazzarella, Carmine Sellitto, Angela Lucariello, Raffaele Melina, Salvatore Iaquinto, Antonio De Luca, Vera Rotondi Aufiero

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Antibiotics (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Gaetano IaquintoGastroenterology Unit, St. Rita Hospital, 83042 Atripalda, Italy.
Giuseppe MazzarellaInstitute of Food Sciences, Consiglio Nazionale Delle Ricerche (CNR), 83100 Atripalda, Italy.ORCID 0000-0002-7294-8277
Carmine SellittoSection of Human Anatomy, Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-5595-7841
Angela LucarielloDepartment of Sport Sciences and Wellness, University of Naples "Parthenope", 80100 Naples, Italy.ORCID 0000-0001-6435-7680
Raffaele MelinaGastroenterology Unit, San G. Moscati Hospital, 83100 Atripalda, Italy.
Salvatore IaquintoGastroenterology Unit, St. Filippo Neri Hospital, 00135 Rome, Italy.
Antonio De LucaSection of Human Anatomy, Department of Mental and Physical Health and Preventive Medicine, University of Campania "Luigi Vanvitelli", 80138 Naples, Italy.ORCID 0000-0002-3905-6154
Vera Rotondi AufieroInstitute of Food Sciences, Consiglio Nazionale Delle Ricerche (CNR), 83100 Atripalda, Italy.
Institute of Food Science · ITAzienda Ospedaliera S.Giuseppe Moscati · ITOspedale San Filippo Neri · ITParthenope University of Naples · ITUniversity of Campania "Luigi Vanvitelli" · ITUniversity of Salerno · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Crohn's disease (CD) is a multifactorial chronic disorder that involves a combination of factors, including genetics, immune response, and gut microbiota. Therapy includes salicylates, immunosuppressive agents, corticosteroids, and biologic drugs. International guidelines do not recommend the use of antibiotics for CD patients, except in the case of septic complications. Increasing evidence of the involvement of gut bacteria in this chronic disease supports the rationale for using antibiotics as the primary treatment for active CD. In recent decades, several pathogens have been reported to be involved in the development of CD, but only

Indexed as

antibiotic therapyCrohn’s diseaseEscherichia coliMycobacterium avium paratuberculosis

Identifiers

PMID38391539
PMCPMC10886129
OpenAlexW4391533791

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.