Trial reportInternational journal of obesity (2005)2024
Supplementation with antioxidant micronutrients in pregnant women with obesity: a randomized controlled trial.
Trial report in International journal of obesity (2005), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02802566 (BMI-Based Prenatal Vitamins to Ameliorate Oxidative Stress in Obese Pregnancy), which is not on this map. Cited by 6 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
BMI-Based Prenatal Vitamins to Ameliorate Oxidative Stress in Obese Pregnancy
Who cites it
6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 5 citations in OpenAlex.
- Investigating the association of albuminuria with the incidence of preeclampsia and its predictive capabilities: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2025Pooled it
- Systematic review of interventions in early pregnancy among pregnant individuals at risk for hyperglycemia.American journal of obstetrics & gynecology MFM · 2025Pooled it
- Longitudinal Assessment of Oxidative Stress Biomarkers During Physiological Pregnancy and Their Relevance for Maternal Healthcare.Healthcare (Basel, Switzerland) · 2026Article
- A role for the antioxidants coenzyme Q10 and pyrroloquinoline quinone in mitigating obesity-associated reproductive dysfunction†.Biology of reproduction · 2026Review
- Environmental Nephrotoxicity Across the Life Course: Oxidative Stress Mechanisms and Opportunities for Early Intervention.Antioxidants (Basel, Switzerland) · 2025Review
- A Narrative Review on the Pathophysiology of Preeclampsia.International journal of molecular sciences · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 1 country.
Funding
Abstract
BACKGROUND/
objectiveObesity increases maternal morbidity and adversely affects child health. Maternal inflammation may play a role in adverse outcomes. The objective of this study was to determine whether providing a higher dose of antioxidant micronutrients to pregnant women with obesity would raise concentrations of key antioxidant vitamins and impact inflammation and oxidative stress during pregnancy. SUBJECTS/
methodsThis was a double-blind, randomized controlled trial. We recruited pregnant women with a body mass index (BMI) ≥ 30 kg/m
interventionBoth groups received a standard prenatal vitamin containing the recommended daily allowance of micronutrients in pregnancy. In addition, the intervention group received a supplement with 90 mg vitamin C, 30 αTU vitamin E, 18 mg vitamin B
resultsThe intervention group had higher vit B
conclusionsHigher concentrations of antioxidant vitamins during pregnancy increased specific micronutrients and did not impact maternal inflammation and oxidative stress, which may be related to dosing or type of supplementation provided. CLINICAL
trial registrationClinical Trial Identification Number: NCT02802566; URL of the Registration Site: www. CLINICALTRIALS: gov .
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.