Evidence map›Paper›PMID 38397018›Full record

ArticleInternational journal of molecular sciences2024

Synergistic Anticancer Activity of Plumbagin and Xanthohumol Combination on Pancreatic Cancer Models.

Ranjith Palanisamy, Nimnaka Indrajith Kahingalage, David Archibald, Ilaria Casari, Marco Falasca

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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  9. Frontiers in pharmacology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ranjith PalanisamyMetabolic Signalling Group, Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Perth 6102, Australia.
Nimnaka Indrajith KahingalageMetabolic Signalling Group, Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Perth 6102, Australia.ORCID 0009-0009-0512-388X
David ArchibaldBackreef Oil Pty Ltd., Perth 6015, Australia.
Ilaria CasariMetabolic Signalling Group, Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Perth 6102, Australia.
Marco FalascaMetabolic Signalling Group, Curtin Medical School, Curtin Health Innovation Research Institute, Curtin University, Perth 6102, Australia.ORCID 0000-0002-9801-7235
Curtin University · AUUniversity of Parma · IT

Funding

Backreef Oil NA
6 · The paper itself

Abstract

Among diverse cancers, pancreatic cancer is one of the most aggressive types due to inadequate diagnostic options and treatments available. Therefore, there is a necessity to use combination chemotherapy options to overcome the chemoresistance of pancreatic cancer cells. Plumbagin and xanthohumol, natural compounds isolated from the Plumbaginaceae family and

Indexed as

NaphthoquinonesPancreatic NeoplasmsPropiophenonesAnimalsApoptosisFlavonoidsMicePlant ExtractsProto-Oncogene Proteins c-bcl-2FlavonoidsNaphthoquinonesPlant ExtractsplumbaginPropiophenonesProto-Oncogene Proteins c-bcl-2xanthohumoldrug combinationspancreatic cancerphytochemicalsplumbaginxanthohumol

Identifiers

PMID38397018
PMCPMC10888694
OpenAlexW4391883709

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.