Evidence map›Paper›PMID 38398111›Full record

ArticleCancers2024

Transcriptomic Profiling for Prognostic Biomarkers in Early-Stage Squamous Cell Lung Cancer (SqCLC).

Maja Šutić, Branko Dmitrović, Antonia Jakovčević, Feđa Džubur, Nada Oršolić, Željko Debeljak, Asta Försti, Sven Seiwerth, Luka Brčić, Goran Madzarac and 3 more

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 6 institutions in 3 countries.

Maja ŠutićLaboratory for Advanced Genomics, Division of Molecular Medicine, Ruđer Bošković Institute, 10000 Zagreb, Croatia.
Branko DmitrovićDepartment of Pathology, Faculty of Dental Medicine and Health Osijek, Clinical Medical Center Osijek, 31000 Osijek, Croatia.
Antonia JakovčevićDepartment of Pathology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Feđa DžuburClinical Department for Respiratory Diseases Jordanovac, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Nada OršolićDivision of Animal Physiology, Faculty of Science, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0001-5102-3606
Željko DebeljakClinical Institute of Laboratory Diagnostics, University Hospital Center Osijek, 31000 Osijek, Croatia.
Asta FörstiHopp Children's Cancer Center (KiTZ), 69120 Heidelberg, Germany.ORCID 0000-0002-9857-4728
Sven SeiwerthDepartment of Pathology, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Luka BrčićDiagnostic and Research Institute of Pathology, Medical University of Graz, 8010 Graz, Austria.ORCID 0000-0002-9098-8416
Goran MadzaracDepartment for Thoracic Surgery, University Hospital Zagreb, 10000 Zagreb, Croatia.
Miroslav SamaržijaClinical Department for Respiratory Diseases Jordanovac, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.
Marko JakopovićClinical Department for Respiratory Diseases Jordanovac, University Hospital Centre Zagreb, School of Medicine, University of Zagreb, 10000 Zagreb, Croatia.ORCID 0000-0002-4815-7512
Jelena KneževićLaboratory for Advanced Genomics, Division of Molecular Medicine, Ruđer Bošković Institute, 10000 Zagreb, Croatia.ORCID 0000-0002-3152-3563
University Hospital Centre Zagreb · HRUniversity of Zagreb · HRRuđer Bošković Institute · HRUniversity of Osijek · HRGerman Cancer Research Center · DEMedical University of Graz · AT

Funding

Croatian Science Foundation IP-2016-06-1441
6 · The paper itself

Abstract

Squamous cell lung carcinoma (SqCLC) is associated with high mortality and limited treatment options. Identification of therapeutic targets and prognostic biomarkers is still lacking. This research aims to analyze the transcriptomic profile of SqCLC samples and identify the key genes associated with tumorigenesis, overall survival (OS), and a profile of the tumor-infiltrating immune cells. Differential gene expression analysis, pathway enrichment analysis, and Gene Ontology analysis on RNA-seq data obtained from FFPE tumor samples (

Indexed as

biomarkersmRNANSCLCprofilingsquamous cell lung cancer (SqCLC)survivalT cellstumor microenvironment (TME)

Identifiers

PMID38398111
PMCPMC10887138
OpenAlexW4391683311

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.