Evidence map›Paper›PMID 38398304›Full record

ArticleJournal of clinical medicine2024

Integrated Machine Learning Approach for the Early Prediction of Pressure Ulcers in Spinal Cord Injury Patients.

Yuna Kim, Myungeun Lim, Seo Young Kim, Tae Uk Kim, Seong Jae Lee, Soo-Kyung Bok, Soojun Park, Youngwoong Han, Ho-Youl Jung, Jung Keun Hyun

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Yuna KimDepartment of Rehabilitation Medicine, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.
Myungeun LimDigital Biomedical Research Division, Electronics and Telecommunications Research Institute, Daejeon 34129, Republic of Korea.ORCID 0000-0003-4409-8890
Seo Young KimDepartment of Rehabilitation Medicine, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.
Tae Uk KimDepartment of Rehabilitation Medicine, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.
Seong Jae LeeDepartment of Rehabilitation Medicine, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.ORCID 0000-0001-7867-4695
Soo-Kyung BokDepartment of Rehabilitation Medicine, College of Medicine, Chungnam National University, Daejeon 35015, Republic of Korea.
Soojun ParkDigital Biomedical Research Division, Electronics and Telecommunications Research Institute, Daejeon 34129, Republic of Korea.
Youngwoong HanDigital Biomedical Research Division, Electronics and Telecommunications Research Institute, Daejeon 34129, Republic of Korea.ORCID 0000-0001-6418-7730
Ho-Youl JungDigital Biomedical Research Division, Electronics and Telecommunications Research Institute, Daejeon 34129, Republic of Korea.ORCID 0000-0002-4467-6307
Jung Keun HyunDepartment of Rehabilitation Medicine, College of Medicine, Dankook University, Cheonan 31116, Republic of Korea.ORCID 0000-0001-9254-4424
Dankook University · KRElectronics and Telecommunications Research Institute · KRChungnam National University · KR

Funding

Electronics and Telecommunications Research Institute 21YR2410National Research Foundation of Korea 2019R1A6A1A11034536National Research Foundation of Korea RS-2023-00208315
6 · The paper itself

Abstract

(1) Background: Pressure ulcers (PUs) substantially impact the quality of life of spinal cord injury (SCI) patients and require prompt intervention. This study used machine learning (ML) techniques to develop advanced predictive models for the occurrence of PUs in patients with SCI. (2) Methods: By analyzing the medical records of 539 patients with SCI, we observed a 35% incidence of PUs during hospitalization. Our analysis included 139 variables, including baseline characteristics, neurological status (International Standards for Neurological Classification of Spinal Cord Injury [ISNCSCI]), functional ability (Korean version of the Modified Barthel Index [K-MBI] and Functional Independence Measure [FIM]), and laboratory data. We used a variety of ML methods-a graph neural network (GNN), a deep neural network (DNN), a linear support vector machine (SVM_linear), a support vector machine with radial basis function kernel (SVM_RBF), K-nearest neighbors (KNN), a random forest (RF), and logistic regression (LR)-focusing on an integrative analysis of laboratory, neurological, and functional data. (3) Results: The SVM_linear algorithm using these composite data showed superior predictive ability (area under the receiver operating characteristic curve (AUC) = 0.904, accuracy = 0.944), as demonstrated by a 5-fold cross-validation. The critical discriminators of PU development were identified based on limb functional status and laboratory markers of inflammation. External validation highlighted the challenges of model generalization and provided a direction for future research. (4) Conclusions: Our study highlights the importance of a comprehensive, multidimensional data approach for the effective prediction of PUs in patients with SCI, especially in the acute and subacute phases. The proposed ML models show potential for the early detection and prevention of PUs, thus contributing substantially to improving patient care in clinical settings.

Indexed as

laboratory testmachine learningprediction modelpressure ulcerspinal cord injury

Identifiers

PMID38398304
PMCPMC10889422
OpenAlexW4391692547

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.