Evidence map›Paper›PMID 38398366›Full record

ArticleJournal of clinical medicine2024

Prognostic Impact of Induced Natriuresis in Acute Decompensated Heart Failure and Its Association with Intraabdominal Pressure and Other Congestion Markers: A Multimodal Approach to Congestion Assessment.

Silvia Crespo-Aznarez, Amelia Campos-Saenz de Santamaría, Marta Sánchez-Marteles, Claudia Josa-Laorden, Fernando Ruiz-Laiglesia, Beatriz Amores-Arriaga, Vanesa Garcés-Horna, Ruben Tejel-Puisac, María Angel Julián-Ansón, Ignacio Giménez-López and 2 more

Open access · goldAbstract read
In one paragraph

Article in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Silvia Crespo-AznarezInternal Medicine Department, Hospital Clínico Lozano Blesa, 50009 Zaragoza, Spain.ORCID 0000-0002-8470-9396
Amelia Campos-Saenz de SantamaríaInternal Medicine Department, Hospital Clínico Lozano Blesa, 50009 Zaragoza, Spain.
Marta Sánchez-MartelesInternal Medicine Department, Hospital Clínico Lozano Blesa, 50009 Zaragoza, Spain.ORCID 0000-0001-9067-2158
Claudia Josa-LaordenAragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0002-8328-9836
Fernando Ruiz-LaiglesiaInternal Medicine Department, Hospital Clínico Lozano Blesa, 50009 Zaragoza, Spain.ORCID 0000-0003-0438-8834
Beatriz Amores-ArriagaAragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.
Vanesa Garcés-HornaInternal Medicine Department, Hospital Clínico Lozano Blesa, 50009 Zaragoza, Spain.
Ruben Tejel-PuisacClinical Biochemistry Deparment, Hospital Clínico Lozano Blesa, 50009 Zaragoza, Spain.ORCID 0009-0002-0102-0428
María Angel Julián-AnsónClinical Biochemistry Deparment, Hospital Clínico Lozano Blesa, 50009 Zaragoza, Spain.
Ignacio Giménez-LópezAragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0002-6043-4869
Juan Ignacio Pérez-CalvoAragon Health Research Institute (IIS Aragon), 50009 Zaragoza, Spain.ORCID 0000-0003-2361-9941
Jorge Rubio-GraciaInternal Medicine Department, Hospital Clínico Lozano Blesa, 50009 Zaragoza, Spain.ORCID 0000-0002-4769-7154
Hospital Clínico Universitario Lozano Blesa · ESUniversidad de Zaragoza · ESHospital Royo Villanova · ES

Funding

Generalitat Valenciana CIAICO/2022/192Hospital La Fe, Valencia VLC-BIOMED AP2022-16
6 · The paper itself

Abstract

backgroundCongestion is an essential issue in patients with heart failure (HF). Standard treatments do not usually achieve decongestion, and various strategies have been proposed to guide treatment, such as determination of natriuresis. After starting treatment with loop diuretics, we postulate that initial natriuresis might help treatment titration, decongestion, and improve prognosis.

methodsIt was a prospective and observational study. Patients admitted with the diagnosis of HF decompensation were eligible. An assessment of congestion was performed during the first 48 h.

resultsA total of 113 patients were included. A poor diuretic response was observed in 39.8%. After the first 48 h, patients with a greater diuretic response on admission (NaU > 80 mmol/L) showed fewer pulmonary b lines (12 vs. 15;

conclusionsUp to 40% of the patients presented a poorer diuretic response at baseline, translating into worse outcomes. Patients with an optimal diuretic response showed significantly higher abdominal decongestion at 48 h and a better prognosis regarding ACM and/or HF rehospitalizations.

Indexed as

congestiondiuretic responseheart failureintraabdominal pressurenatriuresispoint-of-care ultrasound

Identifiers

PMID38398366
PMCPMC10888634
OpenAlexW4391755933

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.