Evidence map›Paper›PMID 38398849›Full record

ArticleNutrients2024

Indirect Calorimetry-Based Novel Approach for Evaluating Metabolic Flexibility and Its Association with Circulating Metabolic Markers in Middle-Aged Subjects.

Elisabetta Murru, Claudia Manca, Gianfranca Carta, Michele Ruggiu, Roberto Solinas, Roberta Montisci, Leanne Hodson, David Dearlove, Maria Pina Mollica, Filippo Tocco and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Elisabetta MurruDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0002-7394-5780
Claudia MancaDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0002-4081-9550
Gianfranca CartaDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0002-3527-4197
Michele RuggiuClinical Cardiology and Sport Medicine, Department of Medical Science and Public Health, University of Cagliari, 09042 Monserrato, Italy.
Roberto SolinasClinical Cardiology and Sport Medicine, Department of Medical Science and Public Health, University of Cagliari, 09042 Monserrato, Italy.
Roberta MontisciClinical Cardiology and Sport Medicine, Department of Medical Science and Public Health, University of Cagliari, 09042 Monserrato, Italy.
Leanne HodsonOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington, Oxford OX3 7LE, UK.ORCID 0000-0002-2648-6526
David DearloveOxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Headington, Oxford OX3 7LE, UK.
Maria Pina MollicaDepartment of Biology, University of Naples Federico II, 80126 Naples, Italy.
Filippo ToccoClinical Cardiology and Sport Medicine, Department of Medical Science and Public Health, University of Cagliari, 09042 Monserrato, Italy.
Sebastiano BanniDepartment of Biomedical Sciences, University of Cagliari, 09042 Monserrato, Italy.ORCID 0000-0003-4805-1387
University of Cagliari · ITNational Institute for Health Research · GBUniversity of Naples Federico II · ITUniversity of Oxford · GB

Funding

GAL Marghine 2014/2020 84250223785
6 · The paper itself

Abstract

We propose a novel method for assessing metabolic flexibility (MF) through indirect calorimetry. A total of twenty healthy volunteers (10 females; 10 males) aged 45-65 were categorized into a Low-Intensity activity group (LI, 0-1 session of 1 h per week) and a High-Intensity activity group (HI, 5-6 sessions of 2 h per week). Volunteers underwent a stepwise exercise test on a cycle ergometer, connected to a calorimeter, to examine respiratory gas exchange to evaluate peak fatty acid Oxidation (PFO) and peak carbohydrate oxidation (PCO). Circulating peroxisome proliferator-activated receptor α (PPARα) biomarkers, docosahexaenoic acid/eicosapentaenoic acid (DHA/EPA) ratio and

Indexed as

EndocannabinoidsPPAR alphaCalorimetry, IndirectDocosahexaenoic AcidsEicosapentaenoic AcidFemaleHumansMaleMiddle AgedOxidation-ReductionDocosahexaenoic AcidsEicosapentaenoic AcidEndocannabinoidsPPAR alpha2-arachidonoylglycerol (2-AG)endocannabinoid systemindirect calorimetrymetabolic flexibilityN-oleoylethanolamine (OEA)peroxisome proliferator-activated receptor α (PPARα)

Identifiers

PMID38398849
PMCPMC10891777
OpenAlexW4391813232

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.