Evidence map›Paper›PMID 38398943›Full record

ArticleMicromachines2024

Diseased Erythrocyte Enrichment Based on I-Shaped Pillar DLD Arrays.

Yao Lv, Jiangbo Wu, Yongqing He, Jie Liu, Wenyu Zhang, Zihan Yan

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yao LvSchool of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, China.
Jiangbo WuSchool of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, China.ORCID 0000-0002-4536-038X
Yongqing HeChongqing Key Laboratory of Micro-Nano System and Intelligent Sensing, Chongqing Technology and Business University, Chongqing 400067, China.
Jie LiuSchool of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, China.
Wenyu ZhangSchool of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, China.
Zihan YanSchool of Energy and Power Engineering, Lanzhou University of Technology, Lanzhou 730050, China.
Lanzhou University of Technology · CNChongqing Technology and Business University · CN

Funding

2022 Gansu Provincial University Industry Support Plan Project 2022CYZC-21Double First-Class Key Program of Gansu Provincial Department of Education GCJ2022-38Key R&D Program of Gansu Province of China 22YF7GA163National Natural Science Foundation of China 52130607National Natural Science Foundation of China 52366009
6 · The paper itself

Abstract

Enrichment of erythrocytes is a necessary step in the diagnosis of blood diseases. Due to the high deformability and viscosity of erythrocytes, they cannot be regarded as stable point-like solids, so the influence of their deformability on fluid dynamics must be considered. Therefore, by using the special effect of an I-shaped pillar (I-pillar) on erythrocytes, erythrocytes with different deformability can be made to produce different provisional distances in the chip, so as to achieve the separation of the two kinds of erythrocytes. In this study, a microfluidic chip was designed to conduct a control test between erythrocytes stored for a long time and fresh erythrocytes. At a specific flow rate, the different deformable erythrocytes in the chip move in different paths. Then, the influence of erythrocyte deformability on its movement trajectory was analyzed by two-dimensional finite element flow simulation. DLD sorting technology provides a new method for the sorting and enrichment of diseased erythrocytes.

Indexed as

deterministic lateral displacementerythrocyte deformabilityfinite element cell model

Identifiers

PMID38398943
PMCPMC10892238
OpenAlexW4391385598

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.