Evidence map›Paper›PMID 38400051›Full record

ArticleViruses2024

Genomic Analyses of Major SARS-CoV-2 Variants Predicting Multiple Regions of Pathogenic and Transmissive Importance.

Steven W Brugger, Julianne H Grose, Craig H Decker, Brett E Pickett, Mary F Davis

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Steven W BruggerDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.
Julianne H GroseDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0001-8816-6635
Craig H DeckerDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0002-2918-7062
Brett E PickettDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.ORCID 0000-0001-7930-8160
Mary F DavisDepartment of Microbiology and Molecular Biology, Brigham Young University, Provo, UT 84602, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The rapid evolution of SARS-CoV-2 has fueled its global proliferation since its discovery in 2019, with several notable variants having been responsible for increases in cases of coronavirus disease 2019 (COVID-19). Analyses of codon bias and usage in these variants between phylogenetic clades or lineages may grant insights into the evolution of SARS-CoV-2 and identify target codons indicative of evolutionary or mutative trends that may prove useful in tracking or defending oneself against emerging strains. We processed a cohort of 120 SARS-CoV-2 genome sequences through a statistical and bioinformatic pipeline to identify codons presenting evidence of selective pressure as well as codon coevolution. We report the identification of two codon sites in the

Indexed as

COVID-19SARS-CoV-2CodonGenome, ViralGenomicsHumansPhylogenyCodonbioinformaticscodon biascoevolutiongenomicsSARS-CoV-2

Identifiers

PMID38400051
PMCPMC10891864

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.