Evidence map›Paper›PMID 38400688›Full record

ArticleCancer medicine2024

Neighborhood social vulnerability and disparities in time to kidney cancer surgical treatment and survival in Arizona.

Celina I Valencia, Patrick Wightman, Kristin E Morrill, Chiu-Hsieh Hsu, Hina Arif-Tiwari, Eric Kauffman, Francine C Gachupin, Juan Chipollini, Benjamin R Lee, David O Garcia and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
  3. Association Between Social Vulnerability and Clinical Outcomes After Proximal Aortic Surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Celina I ValenciaDepartment of Family and Community Medicine, College of Medicine - Tucson, The University of Arizona, Tucson, Arizona, USA.
Patrick WightmanCenter for Population Health Sciences, The University of Arizona, Tucson, Arizona, USA.
Kristin E MorrillCommunity and Systems Health Science Division, College of Nursing, The University of Arizona, Tucson, Arizona, USA.
Chiu-Hsieh HsuDepartment of Epidemiology and Biostatistics, The University of Arizona, Tucson, Arizona, USA.
Hina Arif-TiwariDepartment of Medical Imaging, The University of Arizona, Tucson, Arizona, USA.
Eric KauffmanDepartment of Urology, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.
Francine C GachupinDepartment of Family and Community Medicine, College of Medicine - Tucson, The University of Arizona, Tucson, Arizona, USA.
Juan ChipolliniDepartment of Urology, The University of Arizona, Tucson, Arizona, USA.
Benjamin R LeeDepartment of Urology, The University of Arizona, Tucson, Arizona, USA.
David O GarciaDepartment of Health Promotion Sciences, The University of Arizona, Tucson, Arizona, USA.
Ken BataiDepartment of Cancer Prevention and Control, Roswell Park Comprehensive Cancer Center, Buffalo, New York, USA.ORCID 0000-0002-0317-1118
University of Arizona · USRoswell Park Comprehensive Cancer Center · US

Funding

Uranium as an Environmental Risk Factor for Cancer Among the NavajoU54CA143924 · NCI · UNIVERSITY OF ARIZONA · PI Melissa Marie Herbst-Kralovetz, JUANITA L. MERCHANT · 2009 to 2026
$26.7M
A Mixed Method to Identify Causes of Kidney Cancer Surgical Disparities in ArizonaR21CA248361 · NCI · UNIVERSITY OF ARIZONA · PI CHIPOLLINI, JUAN · 2020 to 2020
$388k
NCI NIH HHS R21 CA248361NCI NIH HHS U54 CA143924NIH HHS 1R21CA248361-01NIH HHS U54CA143924
6 · The paper itself

Abstract

backgroundHispanics and American Indians (AI) have high kidney cancer incidence and mortality rates in Arizona. This study assessed: (1) whether racial and ethnic minority patients and patients from neighborhoods with high social vulnerability index (SVI) experience a longer time to surgery after clinical diagnosis, and (2) whether time to surgery, race and ethnicity, and SVI are associated with upstaging to pT3/pT4, disease-free survival (DFS), and overall survival (OS).

methodsArizona Cancer Registry (2009-2018) kidney and renal pelvis cases (n = 4592) were analyzed using logistic regression models to assess longer time to surgery and upstaging. Cox-regression hazard models were used to test DFS and OS.

resultsHispanic and AI patients with T1 tumors had a longer time to surgery than non-Hispanic White patients (median time of 56, 55, and 45 days, respectively). Living in neighborhoods with high (≥75) overall SVI increased odds of a longer time to surgery for cT1a (OR 1.54, 95% CI: 1.02-2.31) and cT2 (OR 2.32, 95% CI: 1.13-4.73). Race and ethnicity were not associated with time to surgery. Among cT1a patients, a longer time to surgery increased odds of upstaging to pT3/pT4 (OR 1.95, 95% CI: 0.99-3.84). A longer time to surgery was associated with PFS (HR 1.52, 95% CI: 1.17-1.99) and OS (HR 1.63, 95% CI: 1.26-2.11). Among patients with cT2 tumor, living in high SVI neighborhoods was associated with worse OS (HR 1.66, 95% CI: 1.07-2.57).

conclusionsHigh social vulnerability was associated with increased time to surgery and poor survival after surgery.

Indexed as

Carcinoma, Renal CellKidney NeoplasmsArizonaEthnicityHumansKidneyMinority GroupsSocial Vulnerabilitycancer health disparitiesneighborhood factorsrenal cancersocial determinants of healthtreatment disparities

Identifiers

PMID38400688
PMCPMC10891465
OpenAlexW4392133453

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.