Evidence map›Paper›PMID 38403721›Full record

ArticleMolecular neurobiology2024

Mechanism of HDAC1 Regulating Iron Overload-Induced Neuronal Oxidative Damage After Cerebral Hemorrhage.

Jing Han, Jinnan Zhang, Xiaojuan Yao, Meng Meng, Yahui Wan, Yan Cheng

Abstract read
PubMed Publisher
In one paragraph

Article in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jing HanDepartment of Neurology, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, 300052, China.
Jinnan ZhangDepartment of Neurology, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, 300052, China.
Xiaojuan YaoDepartment of Neurology, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, 300052, China.
Meng MengDepartment of Neurology, Tianjin Medical University General Hospital Airport Hospital, Tianjin, 300000, China.
Yahui WanDepartment of Neurology, Tianjin Medical University General Hospital Airport Hospital, Tianjin, 300000, China.
Yan ChengDepartment of Neurology, Tianjin Medical University General Hospital, 154 Anshan Road, Heping District, Tianjin, 300052, China. cchengyan07@163.com.ORCID http://orcid.org/0009-0003-5428-052X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Iron overload is associated with brain edema in the context of intracerebral hemorrhage (ICH). Here, we investigated the role of histone deacetylase 1 (HDAC1) in mediating oxidative damage induced by iron overload after ICH. Utilizing ICH mouse models and FeCl

Indexed as

Cerebral HemorrhageHistone Deacetylase 1Iron OverloadKruppel-Like Factor 4Mice, Inbred C57BLMicroRNAsNeuronsOxidative StressAcetylationAnimalsCell LineKruppel-Like Transcription FactorsMaleMicePromoter Regions, GeneticHdac1 protein, mouseHistone Deacetylase 1Klf4 protein, mouseKruppel-Like Factor 4Kruppel-Like Transcription FactorsMicroRNAsHDAC1Intracerebral hemorrhageIron overloadNeuronsOxidative damage

Identifiers

PMID38403721

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.